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GAD1: glutamate decarboxylase 1

1 protein, 55 patents, 0 drugs, 0 trials, 5,283 NIH grants and 11,816 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGAD1HGNC
Nameglutamate decarboxylase 1HGNC
NCBI Gene ID2571NCBI Gene
HGNC IDHGNC:4092HGNC
EnsemblENSG00000128683NCBI Gene
AliasesCPSQ1, DEE89, GAD, GAD-67, SCPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q99259Glutamate decarboxylase 15942Ensembl, GeneID, HGNCUniProt

Patents 55

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12636346 B22026-05-264Q99259Espacenet
EP 4698223 A22026-02-2514Q99259Espacenet
JP 2026004568 A2026-01-1447678Q99259Espacenet
JP 2025188191 A2025-12-257Q99259Espacenet
EP 4641201 A22025-10-297513Q99259Espacenet
EP 4641202 A22025-10-295282Q99259Espacenet
WO 2025199149 A12025-09-256013Q99259Espacenet
JP 2025517969 A2025-06-127513Q99259Espacenet
KR 1020250017231 A2025-02-045282Q99259Espacenet
US 12156890 B22024-12-033Q99259Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5283

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK017047Diabetes Research Center442,025NIH's project files
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes402,025NIH's project files
P01AI042288Immune Function and the Progression to Type 1 Diabetes252,025NIH's project files
P30DK116073University of Colorado Anschutz Medical Campus DRC212,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award182,025NIH's project files
P30DK045735Yale Diabetes Research Center132,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)122,025NIH's project files
R01DK108868Insulin specific T cell response shaped by diabetes protective MHC class II molecules122,025NIH's project files
R01EB016089Universal Edited MRS at 3T112,025NIH's project files
U01DK103282Type 1 Diabetes TrialNet Clinical Network Hub112,025NIH's project files

Papers 11816

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818344PubTator, text miningPubMed
42789021PubTator, text miningPubMed
42781218PubTator, text miningPubMed
42761936PubTator, text miningPubMed
42739029PubTator, text miningPubMed
42730847PubTator, text miningPubMed
42726206PubTator, text miningPubMed
42719052PubTator, text miningPubMed
42706086PubTator, text miningPubMed
42697051PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license