ConductScience.org, home

Gene · 25823

TPSG1: tryptase gamma 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. TPSG1: tryptase gamma 1. Genes, record 25823. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25823

On this page

Gene

Symbol
TPSG1
HGNC
Name
tryptase gamma 1
HGNC
NCBI Gene ID
25823
NCBI Gene
HGNC ID
HGNC:14134
HGNC
Ensembl
ENSG00000116176
NCBI Gene
Aliases
PRSS31, TMT, trpA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NRR2Tryptase gamma3210Ensembl, GeneID, HGNC

Source UniProt

Patents8

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468403Q9NRR2Espacenet
EP 4650780 A22025-11-19896Q9NRR2Espacenet
JP 2025517970 A2025-06-12896Q9NRR2Espacenet
US 11446398 B22022-09-2093123Q9NRR2Espacenet
JP 2022524081 A2022-04-27196094Q9NRR2Espacenet
JP 2019054813 A2019-04-11248838Q9NRR2Espacenet
JP 2017121241 A2017-07-13248838Q9NRR2Espacenet
JP 2015516143 A2015-06-08248838Q9NRR2Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,036

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTPSG1 papersNewest fiscal year
R35CA231991Chemical Proteomic Platforms for Radically Expanding Cancer Druggability52025
P30AG062715Wisconsin Alzheimer's Disease Research Center42025
P30AG072975Rush Alzheimer's Disease Research Center42025
P30CA008748Cancer Center Support Grant42025
P30CA134274UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT42025
ZIADE000699Cell surface proteolysis in development, tissue repair, and malignancy42025
P20GM103466HAWAII INBRE V PROGRAM32025
P30CA076292Moffitt Cancer Center Support Grant32025
P41GM108538National Center for Quantitative Biology of Complex Systems32025
R01CA206573Structure and function of Transient Receptor Potential Channels32025

1 to 10 of 1,036Source NIH's project files

See all 1,036 nih grants

Papers1,522

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Oral reading fluency assessment assisted by AI: associations with executive functions and intelligence in schoolchildren.Appl Neuropsychol Child202642708401PubTator, text miningPubMed
A Golgi-localized N-methyltransferase and reversible aldo-keto reductases coordinate dual terminal routes in galanthamine biosynthesis.Plant J202642364649PubTator, text miningPubMed
Transient receptor potential channels in Flaviviridae infection: A comprehensive review.Channels (Austin)202642084851PubTator, text miningPubMed
Effects of Rehabilitation Robot Training on Cognitive Function in Stroke Patients: A Meta-Analysis.J Am Med Dir Assoc202641895706PubTator, text miningPubMed
Acute Effects of High-Velocity Interval Cycling Versus Continuous Moderate-Intensity Cycling on Cognitive Function in Patients with Mild Cognitive Impairment.Brain Sci202641892684PubTator, text miningPubMed
Dose-Response Relationship Between Sleep Regularity Index and Stage-Specific Alzheimer's Disease: Cross-Sectional Evidence from Japanese Adults.Geriatrics (Basel)202641873967PubTator, text miningPubMed
Normative age-related structural brain deviations underlying psychopathology, cognitive impairment and neurological soft signs in schizophrenia spectrum disorders.Transl Psychiatry202641862444PubTator, text miningPubMed
Neuroimaging Correlates of the NIH Toolbox Cognition and Trail Making Tests: Normative Benchmarks in Healthy Aging.Clin Transl Neurosci202641852521PubTator, text miningPubMed
Mistranslation from an endogenous tRNA variant in human pan-genome cell lines.Nucleic Acids Res202641841496PubTator, text miningPubMed
Hereditary Alpha-Tryptasemia and Mastocytosis: What We Know and What We Need To Learn.Curr Allergy Asthma Rep202641801525PubTator, text miningPubMed

1 to 10 of 1,522

See all 1,522 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/25823

GET https://conductscience.org/api/genes/v1/25823/grants?page=2