Gene · 25833
POU2F3: POU class 2 homeobox 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. POU2F3: POU class 2 homeobox 3. Genes, record 25833. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25833
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UKI9 | POU domain, class 2, transcription factor 3 | 436 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58837 | Q9UKI9 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 19724 | Q9UKI9 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15505 | Q9UKI9 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 19724 | Q9UKI9 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15505 | Q9UKI9 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15505 | Q9UKI9 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15344 | Q9UKI9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 65986 | Q9UKI9 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 168957 | Q9UKI9 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15698 | Q9UKI9 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,084
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | POU2F3 papers | Newest fiscal year |
|---|---|---|---|
| U24CA213274 | Coordinating center for the NCI small cell lung cancer research consortium | 34 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 28 | 2025 |
| R35CA263816 | Novel therapeutic development for small cell lung cancer | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| R01CA207295 | DNA damaging therapy and immune response in small cell lung cancer subtypes | 9 | 2025 |
| R01AI109023 | Defining P. falciparum resistance to artemisinin-based combination therapies | 8 | 2025 |
| R01AI124678 | Elucidating the molecular basis of piperaquine resistance in Plasmodium falciparum | 8 | 2025 |
| R37AI050234 | Defining the Role of PfCRT and PfMDR1 as Pleiotropic Mediators of Plasmodium falciparum Multidrug Resistance | 7 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| ZIABC011793 | Exploiting DNA Replicative Stress for Novel Small Cell Lung Cancer Therapies | 5 | 2025 |
1 to 10 of 1,084Source NIH's project files
See all 1,084 nih grantsPapers1,618
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Plasma nucleosome profiling reports on tumor burden and molecular subtypes in small cell lung cancer. | J Clin Invest | 2026 | 42820295 | PubTator, text mining | PubMed |
| Adjunctive diagnostic utility of POU2F3 in predominantly pulmonary high-grade neuroendocrine carcinomas with limited or discordant conventional marker expression: a case-control study. | Front Med (Lausanne) | 2026 | 42774020 | PubTator, text mining | PubMed |
| Case Report: Neuroendocrine-low POU2F3-positive small cell lung cancer presenting as a diagnostically unstable thoracic malignancy. | Front Oncol | 2026 | 42760987 | PubTator, text mining | PubMed |
| Immunohistochemical stratification of bladder small cell carcinoma reveals two major phenotypes with distinct therapeutic biomarker profiles. | Histopathology | 2026 | 42747234 | PubTator, text mining | PubMed |
| OX40 (TNFRSF4) Tracks Immune Infiltration in Small Cell Lung Cancer and Shows a Cohort-Specific, Non-Replicated Association with the POU2F3/SCLC-P Subtype: A Multi-Source In Silico Analysis. | Int J Mol Sci | 2026 | 42737720 | PubTator, text mining | PubMed |
| Molecular Subtyping of Biliary Tract Neuroendocrine Carcinomas: Clinicopathological Features and Prognostic Implications. | Am J Surg Pathol | 2026 | 42733321 | PubTator, text mining | PubMed |
| [Expert Consensus on Immunotherapy for Extensive-stage Small Cell Lung Cancer Based on Molecular Subtyping]. | Zhongguo Fei Ai Za Zhi | 2026 | 42705850 | PubTator, text mining | PubMed |
| Tuft cells contribute to the pathogenesis of human primary and experimental murine Sjögren's disease. | J Dent Sci | 2026 | 42688877 | PubTator, text mining | PubMed |
| Quantitative Immunohistochemical Landscapes and Chemoimmunotherapy Outcomes of ASCL1, NEUROD1, POU2F3, and YAP1 in Pure Small-Cell Lung Cancer: A Pilot Study. | J Clin Med | 2026 | 42652818 | PubTator, text mining | PubMed |
| Proteomic landscape of pan-tissue neuroendocrine carcinomas defines subtype-specific functional architectures, biomarkers and therapeutic targets. | Gut | 2026 | 42648907 | PubTator, text mining | PubMed |
1 to 10 of 1,618
See all 1,618 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/25833
GET https://conductscience.org/api/genes/v1/25833/patents