Gene · 25836
NIPBL: NIPBL cohesin loading factor
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. NIPBL: NIPBL cohesin loading factor. Genes, record 25836. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25836
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6KC79 | Nipped-B-like protein | 2,804 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55781 | Q6KC79 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3170 | Q6KC79 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2731 | Q6KC79 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2731 | Q6KC79 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3170 | Q6KC79 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 477 | Q6KC79 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 57071 | Q6KC79 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 160042 | Q6KC79 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 236216 | Q6KC79 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 236216 | Q6KC79 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,329
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NIPBL papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 7 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 5 | 2025 |
| R01HG003143 | Structural Annotation of the Human Genome | 4 | 2025 |
| T32GM008638 | Medical Genetics Research Training Grant | 4 | 2025 |
| P01AI102853 | Molecular Basis for γδ T Lineage Specification | 3 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 3 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 3 | 2025 |
1 to 10 of 1,329Source NIH's project files
See all 1,329 nih grantsPapers1,575
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Handles on chromosome architecture. | Trends Cell Biol | 2026 | 42823293 | PubTator, text mining | PubMed |
| Unraveling a Rare Diagnosis: Genetically Confirmed Cornelia De Lange Syndrome in an Emirati Female Patient. | Cureus | 2026 | 42819766 | PubTator, text mining | PubMed |
| A splicing factor-cohesin association links RNA processing to cohesin-dependent genome folding. | Cell Rep | 2026 | 42771525 | PubTator, text mining | PubMed |
| Corrigendum to Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL. | J Clin Invest | 2026 | 42741949 | PubTator, text mining | PubMed |
| Ctf18-dependent localization of interstitial telomeric sequence to nuclear pore complexes prevents chromosome fragility. | Nucleic Acids Res | 2026 | 42578369 | PubTator, text mining | PubMed |
| Pioneer transcription factors direct tissue-specific cohesin chromatin entry and three-dimensional genome organization. | Nat Genet | 2026 | 42463888 | PubTator, text mining | PubMed |
| Complimentary Episignature Testing for Variant Reclassification: Case Reports with Variant Classification Guideline Consideration. | Mol Syndromol | 2026 | 42434606 | PubTator, text mining | PubMed |
| Cohesin residence time gates 3D genome response to histone hyperacetylation. | bioRxiv | 2026 | 42427660 | PubTator, text mining | PubMed |
| Whole exome sequencing uncovers genetic syndromes and putative candidate genes underlying orofacial clefts presenting with limb abnormalities in a Sub-Saharan African cohort. | BMC Med Genomics | 2026 | 42415090 | PubTator, text mining | PubMed |
| Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters. | J Cardiovasc Aging | 2026 | 42369572 | PubTator, text mining | PubMed |
1 to 10 of 1,575
See all 1,575 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/25836
GET https://conductscience.org/api/genes/v1/25836/patents