Gene · 2588
GALNS: galactosamine (N-acetyl)-6-sulfatase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GALNS: galactosamine (N-acetyl)-6-sulfatase. Genes, record 2588. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2588
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P34059 | N-acetylgalactosamine-6-sulfatase | 522 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents89
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 270 | P34059 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2674 | P34059 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 992 | P34059 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5748 | P34059 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6449 | P34059 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6449 | P34059 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2674 | P34059 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 5748 | P34059 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 5748 | P34059 | Espacenet |
| US 12201095 B2 | 2025-01-21 | 2 | P34059 | Espacenet |
1 to 10 of 89
See all 89 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,525
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GALNS papers | Newest fiscal year |
|---|---|---|---|
| R01DK067859 | Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity | 14 | 2025 |
| R01HD102545 | Non-invasive functional assessment and pathogenesis of Morquio A | 9 | 2025 |
| R01MH054137 | Structure and Function of Dopamine Receptors | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 6 | 2025 |
| R01DA036596 | Regulation of Neuronal GPCR Signaling | 6 | 2025 |
| R01GM122798 | Biasing CXCR3 Signaling to Modulate the Inflammatory Response | 6 | 2025 |
| R01HL016037 | Molecular Regulation of Cardiovascular 7 TM Receptors | 6 | 2025 |
| R01HL056687 | Mechanisms of Maladaptation in Heart Failure | 6 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
1 to 10 of 2,525Source NIH's project files
See all 2,525 nih grantsPapers3,532
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular basis of mucopolysaccharidosis IVA in a large cohort: genotype-phenotype correlations and reporting of 12 novel GALNS variants. | Hum Mol Genet | 2026 | 42822866 | PubTator, text mining | PubMed |
| GALNS gene variants and clinical severity in pediatric mucopolysaccharidosis type IV: A retrospective cohort study from Duhok, Iraq. | Cell Mol Biol (Noisy-le-grand) | 2026 | 42758108 | PubTator, text mining | PubMed |
| The RAMP3 proximity interactor MYO6 determines spatiotemporal signaling of the GPCR CLR in lymphatic endothelial cells. | Sci Signal | 2026 | 42743267 | PubTator, text mining | PubMed |
| Potential role of 5-HT7 receptor antagonists in the treatment of depression: Pharmacological and bioengineering perspectives. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42700946 | PubTator, text mining | PubMed |
| Morquio syndrome masquerading as juvenile idiopathic Arthritis: A case report. | Radiol Case Rep | 2026 | 42597981 | PubTator, text mining | PubMed |
| In vivo genome-wide CRISPR screens of human T cells in solid tumours. | Nature | 2026 | 42587162 | PubTator, text mining | PubMed |
| Pharmacological and Transcriptomic Exploration of β2-Adrenergic Receptor-Gα15 Signaling in THP-1-Derived Macrophages. | bioRxiv | 2026 | 42327218 | PubTator, text mining | PubMed |
| Correction to "Computational Prediction of Deleterious SNPs in the GALNS Gene Implicated in Morquio A Syndrome (MPS IVA)". | ACS Omega | 2026 | 42255592 | PubTator, text mining | PubMed |
| Characterization of Lysosomal Hydrolases and Transporters and Their Age-Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs. | Clin Pharmacol Ther | 2026 | 42198901 | PubTator, text mining | PubMed |
| Longitudinal Multi-Omics Profiling of Aqueous Humor Implicates GALNS Depletion as a Pro-Fibrotic Mediator of Anti-VEGF Therapy in PDR. | Invest Ophthalmol Vis Sci | 2026 | 42149029 | PubTator, text mining | PubMed |
1 to 10 of 3,532
See all 3,532 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2588
GET https://conductscience.org/api/genes/v1/2588/patents?page=2