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Gene · 259

AMBP: alpha-1-microglobulin/bikunin precursor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AMBP: alpha-1-microglobulin/bikunin precursor. Genes, record 259. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/259

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Gene

Symbol
AMBP
HGNC
Name
alpha-1-microglobulin/bikunin precursor
HGNC
NCBI Gene ID
259
NCBI Gene
HGNC ID
HGNC:453
HGNC
Ensembl
ENSG00000106927
NCBI Gene
Aliases
A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02760Protein AMBP35211Ensembl, GeneID, HGNC

Source UniProt

Patents101

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437147P02760Espacenet
EP 4650780 A22025-11-192446P02760Espacenet
JP 2025147176 A2025-10-06764P02760Espacenet
JP 2025529142 A2025-09-045461P02760Espacenet
US 12371689 B22025-07-295461P02760Espacenet
JP 2025517970 A2025-06-122446P02760Espacenet
JP 2025062604 A2025-04-144288P02760Espacenet
JP 2025028160 A2025-02-28764P02760Espacenet
KR 1020250010750 A2025-01-21764P02760Espacenet
EP 4473314 A22024-12-1126P02760Espacenet

1 to 10 of 101

See all 101 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,738

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAMBP papersNewest fiscal year
R01AG034853Biomarker-Based Diagnostic Algorithms To Prevent, Detect And Guide Treatment Of Kidney Disease In Persons Living With HIV162025
UL1TR001863Yale Clinical and Translational Science Award122025
P30AI027763UCSF-Bay Area Center for AIDS Research62025
U01HL146201Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center62025
P30AI050410The University of North Carolina Center for AIDS Research52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant52025
P30DK017047Diabetes Research Center52025
P30AI050409Center for AIDS Research at Emory University42025
P30ES023515Mount Sinai Center for Health and Environment Across the LifeSpan (HEALS)42025
U01HL146204Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS)42025

1 to 10 of 1,738Source NIH's project files

See all 1,738 nih grants

Papers2,591

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Renal function and urinary tubular biomarker abnormalities in untreated and entecavir- or tenofovir disoproxil fumarate-treated patients with chronic hepatitis B: a retrospective cross-sectional study.
Front Med (Lausanne)202642719150PubTator, text miningPubMed
Identification and validation of oxidative stress-related immune signatures in Hepatitis B Virus associated acute liver failure based on WGCNA and machine learning.PLoS One202642715252PubTator, text miningPubMed
Proximal tubulopathy in adult sickle cell disease: association of alpha-1 microglobulin.Clinics (Sao Paulo)202642685378PubTator, text miningPubMed
Modulating amyloid-β 42 aggregation and neurotoxicity by Kunitz domains and their derived peptides.N Biotechnol202642567407PubTator, text miningPubMed
Surgical Timing, Preoperative Oxygenation, and Sex Are Associated with Oxidative Stress and α1-Microglobulin Response in Neonatal Open-Heart Surgery.Med Sci (Basel)202642506379PubTator, text miningPubMed
Deep Proteomic Analysis With Machine Learning Identifies Aqueous Humor Biomarkers of ADAMTSL4-associated Congenital Ectopia Lentis.Invest Ophthalmol Vis Sci202642423409PubTator, text miningPubMed
Unveiling potential natural promoters of calcium oxalate kidney stones in the urine via anion-exchange chromatography, crystal assays, and proteomics.Mol Cell Biochem202642418121PubTator, text miningPubMed
Newborns with sickle cell trait have distinct peripheral blood molecular signatures across the first week of life.Blood Red Cells Iron202642368247PubTator, text miningPubMed
Reprogramming of Iron and Oxygen Metabolism Across the Spectrum of Primary Aldosteronism.medRxiv202642326790PubTator, text miningPubMed
Proximal tubule reabsorptive dysfunction and risk of cardiovascular death among community-living adults: the HUNT-3 cohort.Eur Heart J Open202642291457PubTator, text miningPubMed

1 to 10 of 2,591

See all 2,591 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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