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Gene · 2591

GALNT3: polypeptide N-acetylgalactosaminyltransferase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GALNT3: polypeptide N-acetylgalactosaminyltransferase 3. Genes, record 2591. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2591

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Gene

Symbol
GALNT3
HGNC
Name
polypeptide N-acetylgalactosaminyltransferase 3
HGNC
NCBI Gene ID
2591
NCBI Gene
HGNC ID
HGNC:4125
HGNC
Ensembl
ENSG00000115339
NCBI Gene
Aliases
GalNAc-T3, HFTC, HFTC1, HHS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14435Polypeptide N-acetylgalactosaminyltransferase 36330Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469248Q14435Espacenet
EP 4641201 A22025-10-2911350Q14435Espacenet
JP 2025529142 A2025-09-041675Q14435Espacenet
US 12371689 B22025-07-291675Q14435Espacenet
JP 2025517969 A2025-06-1211350Q14435Espacenet
WO 2025093745 A12025-05-08164Q14435Espacenet
JP 2025032204 A2025-03-1128852Q14435Espacenet
EP 4461818 A22024-11-1328852Q14435Espacenet
US 12006548 B22024-06-11333Q14435Espacenet
JP 2023058610 A2023-04-2528852Q14435Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants521

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGALNT3 papersNewest fiscal year
ZIADE000649Skeletal Disorders and Mineral Homeostasis Section82025
P30CA036727Buffett Cancer Center Support Grant52025
R01AR041398Novel Molecular Biomarkers of Bone Microarchitecture52025
R01CA200423Chemical Glycoproteomics52025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases42025
U19AG055373Trans-omics Integration of Multi-omics Studies for Osteoporosis42025
ZIADE000713Role of O-glycosylation in Animal Development42025
ZIADE000739Structure and Function of UDP-GalNAc:polypeptide alpha-GalNAc transferases32025
P30AR072581Indiana Core Center for Clinical Research in Musculoskeletal Health22025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 521Source NIH's project files

See all 521 nih grants

Papers840

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Fibroblast growth factor 23 (FGF23): From synthesis to cleavage.Mol Cell Endocrinol202742697502PubTator, text miningPubMed
A Novel Homozygous GALNT3 Deletion in Hyperphosphatemic Familial Tumoral Calcinosis Presenting with Subcutaneous Calcifications and Raynaud's Phenomenon in an Adult Patient: A Case Report.Mol Syndromol202642569695PubTator, text miningPubMed
Mechanistic insights into mutations that cause diseases of phosphate dysregulation.Proc Natl Acad Sci U S A202642555639PubTator, text miningPubMed
Integrating Proteome-Wide Association Studies and Single-Cell Transcriptomics Identifies GSTT2B as a Causal Mediator and Prioritizes COL4A1 in Diabetic Retinopathy.Int J Mol Sci202642511522PubTator, text miningPubMed
APOA1, DEFB103A_DEFB103B and DSG3 Are Novel Circulating Biomarkers of Psoriasis.Int J Mol Sci202642450078PubTator, text miningPubMed
When X Does Not Mark the Spot: Autosomal Dominant and Recessive Forms of Renal Hypophosphatemic Rickets and Osteomalacia.Curr Osteoporos Rep202642412262PubTator, text miningPubMed
Disentangling adiposity-related and non-adiposity-related genetic pathways for type 2 diabetes.medRxiv202642396322PubTator, text miningPubMed
Research progress in the role and mechanism of GALNT3 in human diseases (Review).Biomed Rep202641993969PubTator, text miningPubMed
Clinical and Functional Characterization of Novel GALNT3 Mutations in a Chinese Child with Hyperphosphatemic Familial Tumoral Calcinosis.Int J Mol Sci202641898628PubTator, text miningPubMed
Retraction Note: LINC01296/miR-26a/GALNT3 axis contributes to colorectal cancer progression by regulating O-glycosylated MUC1 via PI3K/AKT pathway.J Exp Clin Cancer Res202641888917PubTator, text miningPubMed

1 to 10 of 840

See all 840 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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