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ASPM: assembly factor for spindle microtubules

1 protein, 25 patents, 0 drugs, 0 trials, 2,842 NIH grants and 6,298 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolASPMHGNC
Nameassembly factor for spindle microtubulesHGNC
NCBI Gene ID259266NCBI Gene
HGNC IDHGNC:19048HGNC
EnsemblENSG00000066279NCBI Gene
AliasesASP, Calmbp1, FLJ10517, FLJ10549, MCPH5NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8IZT6Abnormal spindle-like microcephaly-associated protein3,4770Ensembl, GeneID, HGNCUniProt

Patents 25

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437944Q8IZT6Espacenet
EP 4650780 A22025-11-198221Q8IZT6Espacenet
EP 4641201 A22025-10-298389Q8IZT6Espacenet
EP 4641202 A22025-10-295393Q8IZT6Espacenet
JP 2025535734 A2025-10-282Q8IZT6Espacenet
JP 2025517969 A2025-06-128389Q8IZT6Espacenet
JP 2025517970 A2025-06-128221Q8IZT6Espacenet
JP 2025062604 A2025-04-14932Q8IZT6Espacenet
KR 1020250017231 A2025-02-045393Q8IZT6Espacenet
JP 2022141755 A2022-09-29237Q8IZT6Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2842

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)92,025NIH's project files
R01NS032457Cell Identity Determination in Human Brain: Somatic Mutation and Cell Lineage92,025NIH's project files
P30DA018343Yale/NIDA Neuroproteomics Center62,025NIH's project files
P30DK063491Diabetes Research Center (DRC)62,025NIH's project files
P30CA016672Cancer Center Support Grant52,025NIH's project files
P30CA068485Cancer Center Support Grant42,025NIH's project files
P30DK045735Yale Diabetes Research Center42,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases42,025NIH's project files

Papers 6298

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824130PubTator, text miningPubMed
42814397PubTator, text miningPubMed
42771562PubTator, text miningPubMed
42724844PubTator, text miningPubMed
42650678PubTator, text miningPubMed
42637846PubTator, text miningPubMed
42589070PubTator, text miningPubMed
42576628PubTator, text miningPubMed
42521015PubTator, text miningPubMed
42505602PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license