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Gene · 259307

IL4I1: interleukin 4 induced 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IL4I1: interleukin 4 induced 1. Genes, record 259307. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/259307

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Gene

Symbol
IL4I1
HGNC
Name
interleukin 4 induced 1
HGNC
NCBI Gene ID
259307
NCBI Gene
HGNC ID
HGNC:19094
HGNC
Ensembl
ENSG00000104951
NCBI Gene
Aliases
FIG1, LAAO, LAO, hIL4I1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96RQ9L-amino-acid oxidase5670Ensembl, GeneID, HGNC

Source UniProt

Patents283

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910863Q96RQ9Espacenet
EP 4641203 A22025-10-29374Q96RQ9Espacenet
JP 2025147176 A2025-10-067085Q96RQ9Espacenet
JP 2025529142 A2025-09-046738Q96RQ9Espacenet
US 12371689 B22025-07-296738Q96RQ9Espacenet
JP 2025517967 A2025-06-12374Q96RQ9Espacenet
JP 2025517970 A2025-06-1210863Q96RQ9Espacenet
JP 2025028160 A2025-02-287085Q96RQ9Espacenet
KR 1020250017230 A2025-02-04374Q96RQ9Espacenet
KR 1020250010750 A2025-01-217085Q96RQ9Espacenet

1 to 10 of 283

See all 283 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants571

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL4I1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant22025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)22025
P30EY008098Core Grant for Vision Research22025
P40OD010960Viper Resource Grant at Texas A&M University-Kingsville22025
T32NS041218Neural Injury & Plasticity22025
DP1AT012812Charting the evolutionary development of novel genes and the molecular mechanisms of gland tissue organizationin cephalopods12025
DP1DA053731Defining the impact of drug use on immune function and fitness against HIV-112025
I01RX002274Tissue Engineered Total Disc Replacement in a Large Animal Model12025

1 to 10 of 571Source NIH's project files

See all 571 nih grants

Papers1,862

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular Heterogeneity in Clinically Ambiguous Atopic Dermatitis-Psoriasis Overlap: Compartment-Resolved Transcriptomic Profiling.Allergy202642788674PubTator, text miningPubMed
Paired bulk transcriptomic analysis of recurrent glioblastoma with primary single-cell reference mapping.Transl Oncol202642762693PubTator, text miningPubMed
Compensatory pathways in tryptophan metabolism and immune regulation following IDO inhibition.Mol Biol Rep202642730796PubTator, text miningPubMed
Evolution of human IL4I1 preference for aromatic amino acids from a broad-specificity L-amino acid oxidase ancestor.Proc Natl Acad Sci U S A202642585003PubTator, text miningPubMed
Comparative analysis of venom composition, enzymatic activity, and antivenom immunorecognition in neonates of four Bothrops species.Toxicon202642542215PubTator, text miningPubMed
Comparative characterization of Bothrops atrox venom compositional profiles and in vitro activities across distinct localities in the Brazilian Amazon.Toxicon202642526768PubTator, text miningPubMed
Post-Mortem Effects as a Variation Factor in Lachesis muta Venom.Toxins (Basel)202642506708PubTator, text miningPubMed
Association of IL4I1+ M2-like macrophages in tumor microenvironment with poor prognosis in hepatocellular carcinoma: insights from bioinformatics and experimental validation.Front Immunol202642495641PubTator, text miningPubMed
Disruption of macrophage migration inhibitory factor signaling induces major tumor-associated macrophage phenotypes in human M2 macrophages.Mol Biomed202642467313PubTator, text miningPubMed
Benchmarking AI Protein Structure Predictors Reveals a Persistent Bias in Multi-State Proteins.bioRxiv202642465357PubTator, text miningPubMed

1 to 10 of 1,862

See all 1,862 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/259307

GET https://conductscience.org/api/genes/v1/259307/patents?page=2