Gene · 25937
WWTR1: WW domain containing transcription regulator 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. WWTR1: WW domain containing transcription regulator 1. Genes, record 25937. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25937
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9GZV5 | WW domain-containing transcription regulator protein 1 | 400 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents80
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12653785 B2 | 2026-06-16 | 1 | Q9GZV5 | Espacenet |
| EP 4724572 A1 | 2026-04-15 | 3 | Q9GZV5 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7806 | Q9GZV5 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7806 | Q9GZV5 | Espacenet |
| EP 4424837 A2 | 2024-09-04 | 13 | Q9GZV5 | Espacenet |
| US 11976302 B2 | 2024-05-07 | 13 | Q9GZV5 | Espacenet |
| US 11672795 B2 | 2023-06-13 | 1 | Q9GZV5 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 6020 | Q9GZV5 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 8229 | Q9GZV5 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 8235 | Q9GZV5 | Espacenet |
1 to 10 of 80
See all 80 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,305
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | WWTR1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 36 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 22 | 2025 |
| P50CA217694 | SPORE in Soft Tissue Sarcoma | 12 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 8 | 2025 |
| R01HL092961 | Epithelial-Mesenchymal Interactions in Fibrosis Resolution | 8 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 6 | 2025 |
| P30DK026743 | UCSF Liver Center | 6 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| T32HL007035 | Biology of the Lung: A Multidisciplinary Program | 5 | 2025 |
| K08EY031755 | Investigating mechanosensation in the glaucomatous optic nerve head | 4 | 2025 |
1 to 10 of 1,305Source NIH's project files
See all 1,305 nih grantsPapers2,228
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular Distinctions, Diagnosis, and Mechanism-Based Therapies in Lipedema and Obesity. | Curr Issues Mol Biol | 2026 | 42793248 | PubTator, text mining | PubMed |
| Hippo-YAP/TAZ signaling in gastric cancer: orchestrating epithelial-stromal heterogeneity, plasticity, and therapy resistance. | Cancer Heterog Plast | 2026 | 42770147 | PubTator, text mining | PubMed |
| Ciliary Ift20 and Wwtr1 Coordinate Transforming Growth Factor-β Receptor II Signaling to Maintain Bone-Fat Balance in Skeletal Homeostasis. | MedComm (2020) | 2026 | 42769548 | PubTator, text mining | PubMed |
| Integrative transcriptomic, spatial and functional-genomic analysis identifies a UFMylation-related vascular-stromal program and prioritizes WWTR1 in glioblastoma. | Funct Integr Genomics | 2026 | 42747617 | PubTator, text mining | PubMed |
| From Stone to Sponge: Hippo/YAP Mechanotransduction Empowers Cell Fates and Functions in Bone and Liver. | Cold Spring Harb Perspect Biol | 2026 | 42697695 | PubTator, text mining | PubMed |
| Safety Lessons for YAP/TAZ-TEAD Inhibition: From Mechanism to Translation. | Cold Spring Harb Perspect Biol | 2026 | 42697694 | PubTator, text mining | PubMed |
| Aberrant SOX9 expression mediated by protumour macrophages predicts poorer clinical outcomes in hepatoblastoma. | J Pathol | 2026 | 42657494 | PubTator, text mining | PubMed |
| Co-localization of TAZ and H2A.Z up-regulates IL-6 expression in alveolar epithelial cells to polarize M2 cells to alleviate hypoxia-induced lung injury. | Genes Dis | 2026 | 42620447 | PubTator, text mining | PubMed |
| The phosphoproteome of ovarian carcinoma delineates signaling signatures and potentially druggable targets across histotype stages. | NPJ Precis Oncol | 2026 | 42601376 | PubTator, text mining | PubMed |
| Potential Ferroptosis-Related Genes and Immune Infiltration in Form-Deprivation Myopia: An Integrative Bioinformatics and in vitro Validation Study. | Int J Gen Med | 2026 | 42577931 | PubTator, text mining | PubMed |
1 to 10 of 2,228
See all 2,228 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/25937
GET https://conductscience.org/api/genes/v1/25937/patents?page=2