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Gene · 25939

Papers2,857

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Modeling calcific aortic valve disease with engineered human valve tissues identifies SAMHD1 as a therapeutic target.Biomaterials202742501740PubTator, text miningPubMed
Nucleotide metabolic reprogramming: a "double-edged sword" in obesity-related inflammation-from metabolic adaptation to pathological imbalance.J Physiol Biochem202642799975PubTator, text miningPubMed
The interaction between HIV-1 central polypurine tract and host SAMHD1 dNTPase during HIV-1 vector transduction in human primary nondividing monocyte-derived macrophages.Virus Genes202642722809PubTator, text miningPubMed
Single-cell and spatial transcriptomics define eosinophil heterogeneity during influenza A virus-induced exacerbation of fungal allergic asthma in C57BL/6 mice.J Leukoc Biol202642707006PubTator, text miningPubMed
Iterative genetic testing identifies SAMHD1 deficiency caused by a homozygous balanced translocation.J Hum Immun202642657394PubTator, text miningPubMed
p21 (CDKN1A) Is the Major Driver of Sulforaphane-Mediated Reduction in SAMHD1 T592 Phosphorylation in Macrophages.Biomolecules202642650879PubTator, text miningPubMed
SAMHD1 enhances HIV-1-induced glycolysis in monocytic cells through hexokinase 2 upregulation.bioRxiv202642619998PubTator, text miningPubMed
Type I Interferonopathies in the Differential Diagnosis of Vasculitis: A Comprehensive Review.J Vis Exp202642611810PubTator, text miningPubMed
Transition Metal Activation Reframes SAMHD1 Regulation.ACS Chem Biol202642457644PubTator, text miningPubMed
TLR3 activation of microglia-containing cerebral organoid induces antiviral factors against HIV-1 infection.Front Pharmacol202642453569PubTator, text miningPubMed
Entosis remodels the immune microenvironment of osteosarcoma by regulating macrophage polarization: An integrated study based on multi-omics data and in vitro experiments.Transl Oncol202642407378PubTator, text miningPubMed
Early brain-penetrant immunotherapy reverses interferon signature and improves motor outcome in a case of ADAR1-related Aicardi-Goutières syndrome.Clin Transl Immunology202642376186PubTator, text miningPubMed
A toxic STING-SAMHD1 axis drives replication stress in progeria and cancer cells.Nucleic Acids Res202642306943PubTator, text miningPubMed
Genetic and transcriptomic signatures of host control in HIV-1 infection.Retrovirology202642304468PubTator, text miningPubMed
A genomic structural equation modelling analysis of the shared genetic architecture of the aging spine.Eur Spine J202642237046PubTator, text miningPubMed
Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells.PLoS Pathog202642234672PubTator, text miningPubMed
Functionalist Oncology to Model the Contextuality of Dynamics and Treatment in Acute Myeloid Leukaemia.IET Syst Biol202642224255PubTator, text miningPubMed
A homozygous splice-site variant in SAMHD1 shows variable expressivity of Aicardi-Goutières syndrome type 5: a case report and literature review.Front Pediatr202642221009PubTator, text miningPubMed
Human Immunodeficiency Virus Type 2 Vpx-mediated Degradation of TASOR Activates Innate Immune Sensing of Nucleic Acids in Infected Cells.J Mol Biol202642190982PubTator, text miningPubMed
A cell-impermeable kinase inhibitor uncovers outside-in signaling pathways that promote HIV-1 infection.J Virol202642112903PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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