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Gene · 25942

SIN3A: SIN3 transcription regulator family member A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SIN3A: SIN3 transcription regulator family member A. Genes, record 25942. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25942

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Gene

Symbol
SIN3A
HGNC
Name
SIN3 transcription regulator family member A
HGNC
NCBI Gene ID
25942
NCBI Gene
HGNC ID
HGNC:19353
HGNC
Ensembl
ENSG00000169375
NCBI Gene
Aliases
CHR15DELq24, DEL15Q24, DKFZP434K2235, KIAA0700, WITKOS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96ST3Paired amphipathic helix protein Sin3a1,2730Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463626Q96ST3Espacenet
JP 2026004568 A2026-01-1463627Q96ST3Espacenet
JP 2026004568 A2026-01-1463628Q96ST3Espacenet
EP 4641201 A22025-10-297858Q96ST3Espacenet
JP 2025517969 A2025-06-127858Q96ST3Espacenet
US 11446398 B22022-09-2079267Q96ST3Espacenet
US 11446398 B22022-09-2079268Q96ST3Espacenet
US 11446398 B22022-09-2079269Q96ST3Espacenet
JP 2022524081 A2022-04-27182238Q96ST3Espacenet
JP 2022524081 A2022-04-27182239Q96ST3Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,893

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSIN3A papersNewest fiscal year
P30CA008748Cancer Center Support Grant192025
P30CA068485Cancer Center Support Grant142025
P30CA042014Cancer Center Support Grant132025
P30CA016672Cancer Center Support Grant122025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology122025
P30CA021765Cancer Center Support Grant (CCSG)112025
P30CA016087Cancer Center Support Grant102025
P30DK054759Precision Medicine Center for Cystic Fibrosis92025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82025
ZIADK060101Targeted disruption the enzymes of O-GlcNAc cycling: Animal models of Disease72025

1 to 10 of 2,893Source NIH's project files

See all 2,893 nih grants

Papers3,655

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
REST in the Central Nervous System: Context-Dependent Regulation of Neuronal Homeostasis and Disease.Int J Dev Neurosci202642827376PubTator, text miningPubMed
Multicomplex Integrative Structural Modeling of a Human Histone Deacetylase Interactome.Mol Cell Proteomics202642680104PubTator, text miningPubMed
Global genetic modifiers of fetal hemoglobin in sickle cell disease: Systematic review and meta-analysis.iScience202642657270PubTator, text miningPubMed
UNCX/SIN3A-Mediated H4K8 decrotonylation suppresses FOXO3 to drive TNBC progression and docetaxel resistance.Cell Signal202642586287PubTator, text miningPubMed
CRISPR-PITA: An Imaging-Based CRISPR/dCas9 Assay to Determine Recruitment Directionality of Nuclear Proteins.Bio Protoc202642427447PubTator, text miningPubMed
Transcriptional repression by TGIF2 coordinates neurogenic priming and neural stem cell maintenance.Sci Adv202642361180PubTator, text miningPubMed
Predicting the Impact of Deleterious Single-Nucleotide Polymorphisms in the p47ING1a Isoform of Human ING1 Gene.Genet Res (Camb)202642322085PubTator, text miningPubMed
Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.Res Sq202642281995PubTator, text miningPubMed
A Novel Emerin/Nesprin-3 Interaction Mediates Nuclear Size Changes Induced by Oncogenic KRAS in Pancreatic Cancer Cells.Mol Cell Biol202642175908PubTator, text miningPubMed
Unraveling the layers of epigenetic control in respiratory antiviral defense.J Virol202642159289PubTator, text miningPubMed

1 to 10 of 3,655

See all 3,655 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/25942

GET https://conductscience.org/api/genes/v1/25942/patents?page=2