Gene · 25996
REXO2: RNA exonuclease 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. REXO2: RNA exonuclease 2. Genes, record 25996. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/25996
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y3B8 | Oligoribonuclease, mitochondrial | 237 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 61602 | Q9Y3B8 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2534 | Q9Y3B8 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2534 | Q9Y3B8 | Espacenet |
| US 12084509 B2 | 2024-09-10 | 10 | Q9Y3B8 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 75520 | Q9Y3B8 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 75530 | Q9Y3B8 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 178491 | Q9Y3B8 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 178501 | Q9Y3B8 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 9509 | Q9Y3B8 | Espacenet |
| JP 2021018154 A | 2021-02-15 | 845 | Q9Y3B8 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants886
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | REXO2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| P01CA100730 | Retrovirus Models of Cancer | 6 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 3 | 2025 |
| P30CA014236 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 886Source NIH's project files
See all 886 nih grantsPapers1,535
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cytologic Sub-Categorization of Bethesda Category IV Nodules Has Significant Clinicopathologic Outcomes. | Cytopathology | 2026 | 42827277 | PubTator, text mining | PubMed |
| AI-powered histopathology classifiers identify transcriptomic biomarkers associated with cell cycle regulation and increased mitotic activity in poorly differentiated neuroendocrine carcinoma. | Hum Genomics | 2026 | 42800881 | PubTator, text mining | PubMed |
| Associations of long-term PM2.5 exposure and genetic susceptibility with prevalent metabolic syndrome and subsequent cardiovascular disease risk: A UK Biobank cohort study. | Ecotoxicol Environ Saf | 2026 | 42743706 | PubTator, text mining | PubMed |
| Exploratory Multi-Platform Bioinformatic Analysis of MEAK7 and Its Molecular, Survival, and Immune Associations in Pancreatic Ductal Adenocarcinoma. | Int J Mol Sci | 2026 | 42737511 | PubTator, text mining | PubMed |
| Cognitive heterogeneity in major depressive disorder: Neuroimaging, transcriptomic, and neurotransmitter profiles. | Psychiatry Clin Neurosci | 2026 | 42704208 | PubTator, text mining | PubMed |
| Loss of epitranscriptomic mitochondrial RNA surveillance drives epithelial type I interferon and inflammation in autoimmunity. | Proc Natl Acad Sci U S A | 2026 | 42636376 | PubTator, text mining | PubMed |
| Des-Gamma-Carboxy Prothrombin Is Associated With Tumor Aggressiveness and Recurrence in Resected Early-Stage Hepatocellular Carcinoma: A Clinicopathological and Molecular Analysis. | Hepatol Res | 2026 | 42592951 | PubTator, text mining | PubMed |
| Stress-specific 14-3-3-client modules in digestive cancers: an evidence-graded review of adaptive survival and therapy resistance. | Cancer Biol Ther | 2026 | 42507757 | PubTator, text mining | PubMed |
| Study on the mechanism of TP53 degradation by SFN ubiquitination affecting locally advanced TC progression. | Front Chem | 2026 | 42444845 | PubTator, text mining | PubMed |
| Hydrogen sulfide modulates gene networks in hypoxia/reoxygenation-stressed trophoblasts: insights from transcriptome profiling. | Front Bioinform | 2026 | 42382641 | PubTator, text mining | PubMed |
1 to 10 of 1,535
See all 1,535 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/25996
GET https://conductscience.org/api/genes/v1/25996/patents