ConductScience.org, home

Gene · 26047

CNTNAP2: contactin associated protein 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. CNTNAP2: contactin associated protein 2. Genes, record 26047. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26047

On this page

Gene

Symbol
CNTNAP2
HGNC
Name
contactin associated protein 2
HGNC
NCBI Gene ID
26047
NCBI Gene
HGNC ID
HGNC:13830
HGNC
Ensembl
ENSG00000174469
NCBI Gene
Aliases
AUTS15, CASPR2, CDFE, Caspr2, KIAA0868, NRXN4, PTHSL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UHC6Contactin-associated protein-like 21,3311Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442212Q9UHC6Espacenet
WO 2025259600 A22025-12-1831Q9UHC6Espacenet
EP 4650780 A22025-11-197942Q9UHC6Espacenet
EP 4641201 A22025-10-298029Q9UHC6Espacenet
JP 2025147176 A2025-10-063161Q9UHC6Espacenet
JP 2025529142 A2025-09-041070Q9UHC6Espacenet
JP 2025529142 A2025-09-045926Q9UHC6Espacenet
US 12371689 B22025-07-291070Q9UHC6Espacenet
US 12371689 B22025-07-295926Q9UHC6Espacenet
JP 2025517969 A2025-06-128029Q9UHC6Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,211

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCNTNAP2 papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award112025
R25MH077823Research Education for Future Physician-Scientists in Child Psychiatry102025
P50HD027802Differential Diagnosis in Learning Disabilities82025
R01NS126227Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep Phenotyping82025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)72025
P50HD052120Learning Disabilities Translational Science Collective: Building on the Florida LDRC52025
P50HD103526MIND Institute Intellectual and Developmental Disabilities Research Center52025
P01AI073693Anti-NMDA Receptor Antibodies in Adult Brain Dysfunction: Lessons from Lupus42025
P30AG066444Alzheimer's Disease Research Center42025
T32MH018268Training Program in Childhood Neuropsychiatric Disorders42025

1 to 10 of 2,211Source NIH's project files

See all 2,211 nih grants

Papers3,932

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Immune dysregulation and epileptogenesis.Neurol Sci202642820995PubTator, text miningPubMed
CNTNAP2 in neurodevelopmental disorders: Genetics, excitation/inhibition mechanisms and preclinical evidence.Mol Cell Neurosci202642815598PubTator, text miningPubMed
Beyond Nerve Hyperexcitability: Potential Implications of Cerebrospinal Fluid CASPR2 Antibodies for Central Pain Processing in Isaacs Syndrome: A Case-Based Systematic Review.Pain Ther202642809178PubTator, text miningPubMed
Acrodynia and CASPR2 Autoimmunity in Elemental Mercury Toxicity.J Med Toxicol202642804122PubTator, text miningPubMed
Anti-Contactin-Associated Protein-Like-2 Antibody-Positive Morvan Syndrome With Myokymia in Thymoma-Associated Myasthenia Gravis.Neurology202642777187PubTator, text miningPubMed
Antibody-Dependent Cellular Phagocytosis and Cytotoxicity in Patients With LGI1 and CASPR2 Encephalitis.Neurol Neuroimmunol Neuroinflamm202642777167PubTator, text miningPubMed
Posterior reversible encephalopathy syndrome as an initial manifestation of CASPR2-positive Morvan syndrome: a case report.Neurol Sci202642734880PubTator, text miningPubMed
CASPR2 antibody-associated neurological syndrome after PD-1 inhibitor treatment (tislelizumab) in a patient with lung adenocarcinoma: A case report and literature review.J Neuroimmunol202642721852PubTator, text miningPubMed
Autoimmune Encephalitis: A Case Series from a Tertiary Care Center in South India.Neurol India202642700126PubTator, text miningPubMed
Autoimmune-associated epilepsy: definitions and diagnosis - a narrative review.Arq Neuropsiquiatr202642674427PubTator, text miningPubMed

1 to 10 of 3,932

See all 3,932 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/26047

GET https://conductscience.org/api/genes/v1/26047/patents?page=2