Gene · 26121
PRPF31: pre-mRNA processing factor 31
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PRPF31: pre-mRNA processing factor 31. Genes, record 26121. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26121
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8WWY3 | U4/U6 small nuclear ribonucleoprotein Prp31 | 499 | 30 | Ensembl, GeneID, HGNC |
Source UniProt
Patents43
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 281 | Q8WWY3 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 60400 | Q8WWY3 | Espacenet |
| EP 4667578 A2 | 2025-12-24 | 148 | Q8WWY3 | Espacenet |
| EP 4667578 A2 | 2025-12-24 | 149 | Q8WWY3 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5535 | Q8WWY3 | Espacenet |
| JP 2025131621 A | 2025-09-09 | 148 | Q8WWY3 | Espacenet |
| JP 2025131621 A | 2025-09-09 | 149 | Q8WWY3 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5535 | Q8WWY3 | Espacenet |
| WO 2024214081 A1 | 2024-10-17 | 281 | Q8WWY3 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 66451 | Q8WWY3 | Espacenet |
1 to 10 of 43
See all 43 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,434
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PRPF31 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 33 | 2025 |
| P30EY014104 | P30 Core Grant for Vision Research | 11 | 2025 |
| R01EY018213 | Defining Barriers to Gene Therapy | 11 | 2025 |
| R01EY022356 | Molecular Basis of Human Visual System Disorders | 11 | 2025 |
| R01EY012910 | Precision Medicine for Inherited Retinal Degenerations | 10 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 8 | 2025 |
| R01EY018571 | Genetics of early onset retinal diseases | 8 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 7 | 2025 |
1 to 10 of 2,434Source NIH's project files
See all 2,434 nih grantsPapers3,060
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Protective effects of sarcopenia-related traits on spinal degenerative diseases: A large prospective cohort study. | Bone | 2027 | 42790802 | PubTator, text mining | PubMed |
| From splice defect to therapeutic opportunity: Insights from PRPF31. | Mol Ther | 2026 | 42822454 | PubTator, text mining | PubMed |
| Cell-autonomous restoration of splicing homeostasis and RP11 phenotype in patient-derived RPE and retinal organoids by PRPF31.AAV gene therapy. | Nat Commun | 2026 | 42816512 | PubTator, text mining | PubMed |
| Functional Genomic Screening Identifies lncRNA CNPY2-AS1 as a Regulator of Redox Metabolism and Antiviral Immunity. | Int J Biol Sci | 2026 | 42807861 | PubTator, text mining | PubMed |
| A novel PRPF31 variant associated with autosomal dominant retinitis pigmentosa in Japanese families. | Ophthalmic Genet | 2026 | 42768956 | PubTator, text mining | PubMed |
| Genome-wide association meta-analysis of eating behavior traits revealed one susceptibility locus for emotional eating. | Mol Psychiatry | 2026 | 42736351 | PubTator, text mining | PubMed |
Overexpression of the Yes-associated Protein 1 Promoter-associated Long Noncoding RNA RP11-732A21.3 Enhances E-cadherin-dependent Cellular Cohesiveness during Anchorage-independent Growth in Colon Cancer. | J Physiol Investig | 2026 | 42725672 | PubTator, text mining | PubMed |
| Mesenchymal drift in ciliopathy iPSC-derived RPE reveals a convergent pathogenic cell state. | Cell Rep | 2026 | 42667617 | PubTator, text mining | PubMed |
| Non-syndromic adult-onset rod-cone dystrophy. | Retina | 2026 | 42627262 | PubTator, text mining | PubMed |
| Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output. | Cold Spring Harb Perspect Biol | 2026 | 42575696 | PubTator, text mining | PubMed |
1 to 10 of 3,060
See all 3,060 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/26121
GET https://conductscience.org/api/genes/v1/26121/patents?page=2