Gene · 2617
GARS1: glycyl-tRNA synthetase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GARS1: glycyl-tRNA synthetase 1. Genes, record 2617. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2617
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P41250 | Glycine--tRNA ligase | 739 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48078 | P41250 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10671 | P41250 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11067 | P41250 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5797 | P41250 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6459 | P41250 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6459 | P41250 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11067 | P41250 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10671 | P41250 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 5797 | P41250 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 5797 | P41250 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants996
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GARS1 papers | Newest fiscal year |
|---|---|---|---|
| R35GM139627 | Link extracellular function of tRNA synthetase with pathological mechanism of disease | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 4 | 2025 |
| R35GM146860 | Understanding higher-order glycine receptor assemblies in neurotransmission | 3 | 2025 |
| R37NS054154 | The Genetics of the Neuromuscular Junction: Mechanisms and Disease Models | 3 | 2025 |
| ZIAAA000407 | Synaptic Transmission: Modulation, Plasticity And Effects Of Drugs Of Abuse | 3 | 2025 |
| ZIBHG000196 | Inter- and Intra-Species Comparative Sequencing | 3 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 2 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 2 | 2025 |
1 to 10 of 996Source NIH's project files
See all 996 nih grantsPapers1,667
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Convergent TBK1 loss of function drives gasdermin E dependent pyroptosis and motor neuron degeneration across ALS genotypes. | Cell Death Differ | 2026 | 42768102 | PubTator, text mining | PubMed |
| Case Report: Acute interstitial pneumonia as the initial presentation of Anti-EJ antisynthetase syndrome: a case of severe respiratory failure with rapid response to cyclophosphamide. | Front Immunol | 2026 | 42656765 | PubTator, text mining | PubMed |
| Synaptic vs. Non-Synaptic Glycine Receptors: Physiological Role and Implications in Alzheimer's Disease Pathology. | Int J Mol Sci | 2026 | 42511649 | PubTator, text mining | PubMed |
| Identification of potential key genes that respond to capsaicin treatment in ER-positive breast cancer: An integrated analysis. | PLoS One | 2026 | 42234642 | PubTator, text mining | PubMed |
| A non-proteolytic role of SARS-CoV-2 PLpro in modulating host glycyl-tRNA synthetase activity. | J Mol Cell Biol | 2026 | 42133471 | PubTator, text mining | PubMed |
| Locally synthesized glycyl aminoacyl-tRNA synthetase is important for local translation in neurons. | Life Sci Alliance | 2026 | 41986236 | PubTator, text mining | PubMed |
| Structural basis of human zinc-activated channel (ZAC) signaling and modulation. | Cell Discov | 2026 | 41912481 | PubTator, text mining | PubMed |
Pharmacogenomic-Based GWAS Meta-Analyses Coupled with Genetic and Epigenetic Liability Testing Connects Facial and Emotional Recognition Systems to Spectrum Disorders, Schizophrenia, Depression, and Anxiety. | Curr Pharm Biotechnol | 2026 | 41830575 | PubTator, text mining | PubMed |
| Weaker neuroligin 2-neurexin β1 interaction tethers membranes and recruits gephyrin at membrane junctions through clustering. | Sci Adv | 2026 | 41824561 | PubTator, text mining | PubMed |
| Glycine receptors in circulating white blood cells regulated by neuroinflammation. | Front Immunol | 2026 | 41808824 | PubTator, text mining | PubMed |
1 to 10 of 1,667
See all 1,667 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2617
GET https://conductscience.org/api/genes/v1/2617/patents?page=2