Gene · 2621
GAS6: growth arrest specific 6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GAS6: growth arrest specific 6. Genes, record 2621. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2621
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14393 | Growth arrest-specific protein 6 | 678 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents85
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48293 | Q14393 | Espacenet |
| JP 2026000906 A | 2026-01-06 | 93 | Q14393 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5930 | Q14393 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 862 | Q14393 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5657 | Q14393 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5800 | Q14393 | Espacenet |
| KR 1020250136262 A | 2025-09-16 | 63 | Q14393 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6461 | Q14393 | Espacenet |
| EP 4602062 A1 | 2025-08-20 | 7 | Q14393 | Espacenet |
| US 12384822 B2 | 2025-08-12 | 7 | Q14393 | Espacenet |
1 to 10 of 85
See all 85 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| BATIRAXCEPT | CHEMBL4594462 | Growth arrest-specific protein 6 inhibitor | INHIBITOR |
Source ChEMBL
Trials9
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT05826015 | BATIRAXCEPT | PHASE1 | ClinicalTrials.gov | |
| NCT04983407 | BATIRAXCEPT | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT04729608 | BATIRAXCEPT | PHASE3 | ClinicalTrials.gov | |
| NCT04300140 | BATIRAXCEPT | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT04042623 | BATIRAXCEPT | PHASE2 | 2022-02-10 | ClinicalTrials.gov |
| NCT04019288 | BATIRAXCEPT | PHASE1/PHASE2 | 2025-06-11 | ClinicalTrials.gov |
| NCT04004442 | BATIRAXCEPT | PHASE1 | ClinicalTrials.gov | |
| NCT03639246 | BATIRAXCEPT | PHASE1 | ClinicalTrials.gov | |
| NCT03607955 | BATIRAXCEPT | PHASE1 | ClinicalTrials.gov |
NIH grants2,018
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GAS6 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 25 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 20 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 16 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 10 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 9 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 7 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 7 | 2025 |
| K12HD000849 | Reproductive Scientist Development Program | 6 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 6 | 2025 |
1 to 10 of 2,018Source NIH's project files
See all 2,018 nih grantsPapers3,604
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Therapy-educated fibroblast states link treatment pressure to residual disease and acquired resistance in gastric cancer. | Front Immunol | 2026 | 42812889 | PubTator, text mining | PubMed |
| Remote Ischemic Post-Conditioning Preserves the Neurovascular Unit by Brain-Derived Gas6 That Drives Monocyte-Derived Macrophage Reprogramming via Axl and Vimentin after SAH. | Adv Sci (Weinh) | 2026 | 42801717 | PubTator, text mining | PubMed |
| Aberrant expression of MERTK activates BCR via CD79a in CLL cells: alternative therapeutic strategy for relapsed/refractory CLL. | Leukemia | 2026 | 42778661 | PubTator, text mining | PubMed |
| Long non-coding RNA GAS6-AS1 and its molecular mechanisms in human cancer (Review). | Biomed Rep | 2026 | 42769717 | PubTator, text mining | PubMed |
| Single-cell and spatial multi-omics reveal a recurrent multicellular niche at the tumor-stroma interface in multidrug resistance. | Cell Rep Med | 2026 | 42748914 | PubTator, text mining | PubMed |
| AXL mediates influenza A virus entry and drives virus-induced inflammation. | Emerg Microbes Infect | 2026 | 42717575 | PubTator, text mining | PubMed |
| Targeting Compensatory AKT Activation Overcomes Resistance to AXL Inhibition in Acute Lymphoblastic Leukemia. | Mol Cancer Ther | 2026 | 42704216 | PubTator, text mining | PubMed |
| Rosa damascena-derived nanovesicles restore GAS6-driven efferocytic balance in LPS-induced inflammatory model. | J Drug Target | 2026 | 42698269 | PubTator, text mining | PubMed |
| Context-dependent effects of MIR100HG on tumorigenic phenotypes and p38/MAPK-AKT signaling in hepatocellular carcinoma. | Funct Integr Genomics | 2026 | 42698010 | PubTator, text mining | PubMed |
| Expression of TAM receptors and their ligands in unexplained recurrent pregnancy loss. | Immunol Res | 2026 | 42684543 | PubTator, text mining | PubMed |
1 to 10 of 3,604
See all 3,604 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2621
GET https://conductscience.org/api/genes/v1/2621/patents?page=2