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Gene · 26227

PHGDH: phosphoglycerate dehydrogenase

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. PHGDH: phosphoglycerate dehydrogenase. Genes, record 26227. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/26227

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
PHGDH
HGNC
Name
phosphoglycerate dehydrogenase
HGNC
NCBI Gene ID
26227
NCBI Gene
HGNC ID
HGNC:8923
HGNC
Ensembl
ENSG00000092621
NCBI Gene
Aliases
3-PGDH, 3PGDH, HEL-S-113, NLS, NLS1, PDG, PGAD, PGD, PGDH, PHGDHD, SERA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43175D-3-phosphoglycerate dehydrogenase53321Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4796640 A12026-08-2624O43175Espacenet
JP 2026082974 A2026-05-19138O43175Espacenet
JP 2026067851 A2026-04-21324O43175Espacenet
JP 2026004568 A2026-01-1457842O43175Espacenet
EP 4650780 A22025-11-1919335O43175Espacenet
EP 4641201 A22025-10-2924541O43175Espacenet
EP 4641202 A22025-10-299747O43175Espacenet
JP 2025517969 A2025-06-1224541O43175Espacenet
JP 2025517970 A2025-06-1219335O43175Espacenet
JP 2025510686 A2025-04-151O43175Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,871

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant342025
P30CA016672Cancer Center Support Grant172025
R01CA163591Tumor cell metabolism in action132025
P01CA117969Genetics and Biology of Pancreatic Ductal Adenocarcinoma102025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes102025
P30CA072720Cancer Center Support Grant92025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882025
P30CA016087Cancer Center Support Grant72025
ZIAHL006001Framingham Project/Levy72025
P30CA014051Cancer Center Support (Core) Grant62025

1 to 10 of 2,871Source NIH's project files

See all 2,871 nih grants

Papers4,529

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42812455PubTator, text miningPubMed
42804747PubTator, text miningPubMed
42780918PubTator, text miningPubMed
42774112PubTator, text miningPubMed
42756106PubTator, text miningPubMed
42748656PubTator, text miningPubMed
42737697PubTator, text miningPubMed
42733934PubTator, text miningPubMed
42724467PubTator, text miningPubMed
42684639PubTator, text miningPubMed

1 to 10 of 4,529

See all 4,529 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/26227

GET https://conductscience.org/api/genes/v1/26227/patents?page=2