Gene · 26277
TINF2: TERF1 interacting nuclear factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TINF2: TERF1 interacting nuclear factor 2. Genes, record 26277. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26277
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9BSI4 | TERF1-interacting nuclear factor 2 | 451 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026027383 A | 2026-02-18 | 41 | Q9BSI4 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2614 | Q9BSI4 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13255 | Q9BSI4 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13257 | Q9BSI4 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7891 | Q9BSI4 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7891 | Q9BSI4 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2614 | Q9BSI4 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 13255 | Q9BSI4 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 13257 | Q9BSI4 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 13255 | Q9BSI4 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,403
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TINF2 papers | Newest fiscal year |
|---|---|---|---|
| ZIACP010190 | Genetic Epidemiology of Telomere Maintenance and Cancer Etiology | 30 | 2025 |
| R01AG016642 | Mechanism of the telomeric proliferation limit | 18 | 2025 |
| ZIACP010144 | Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes | 18 | 2025 |
| ZIAHL006089 | Telomere Diseases and Other Constitutional and Acquired Genetic Disorders of Hematopoiesis | 11 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 9 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 6 | 2025 |
| P30ES025128 | Center for Human Health and the Environment (CHHE) | 6 | 2025 |
| R01HL131744 | Molecular Genetics of the Telomere Biology Disorders | 6 | 2025 |
1 to 10 of 1,403Source NIH's project files
See all 1,403 nih grantsPapers1,630
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Military Veteran with Pulmonary Fibrosis, Hepatic Cirrhosis, Bone Marrow Dysfunction and Shortened Telomeres Found to Have GAVE, a Potential Unsuspected Consequence of Telomere Spectrum Disorder. | J Clin Med | 2026 | 42795846 | PubTator, text mining | PubMed |
| First Experience of TCRαβ⁺ Depleted Haploidentical Hematopoietic Stem Cell Transplantation in a Child with a TINF2-Related Telomere Biology Disorder. | Turk J Haematol | 2026 | 42755158 | PubTator, text mining | PubMed |
| Genomic and computational analysis of variants in telomere regulatory genes in subjects with bone marrow failure. | Eur J Hum Genet | 2026 | 42736390 | PubTator, text mining | PubMed |
| Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant. | Pediatr Blood Cancer | 2026 | 42657693 | PubTator, text mining | PubMed |
| Meiotic telomeres of vole B chromosomes: shelterin and associated proteins provide a link to the nuclear envelope. | Chromosome Res | 2026 | 42479255 | PubTator, text mining | PubMed |
| Suspected parental gonadal/gonadosomatic mosaicism for a TINF2 mutation in two sisters with dyskeratosis congenita. | Front Genet | 2026 | 42460152 | PubTator, text mining | PubMed |
| Outcomes of Dyskeratosis Congenita: Results From the Canadian Inherited Marrow Failure Registry. | J Pediatr Hematol Oncol | 2026 | 42267950 | PubTator, text mining | PubMed |
| Telomere maintaining germline and somatic variants in thyroid cancer and melanoma. | medRxiv | 2026 | 42245030 | PubTator, text mining | PubMed |
| A Case of Long-Term Management of Oral Function in a Child with Dyskeratosis Congenita. | Diagnostics (Basel) | 2026 | 42122061 | PubTator, text mining | PubMed |
| Micronuclei: origins, assays, mechanisms, diseases and treatments. | Signal Transduct Target Ther | 2026 | 41888103 | PubTator, text mining | PubMed |
1 to 10 of 1,630
See all 1,630 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/26277
GET https://conductscience.org/api/genes/v1/26277/patents?page=2