Gene · 2633
GBP1: guanylate binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GBP1: guanylate binding protein 1. Genes, record 2633. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2633
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P32455 | Guanylate-binding protein 1 | 592 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48565 | P32455 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8779 | P32455 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8987 | P32455 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 502 | P32455 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8987 | P32455 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8779 | P32455 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 502 | P32455 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 110 | P32455 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36948 | P32455 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 139919 | P32455 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,419
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GBP1 papers | Newest fiscal year |
|---|---|---|---|
| P30AG017265 | USC/UCLA Center on Biodemography and Population Health | 9 | 2025 |
| R01AI139425 | Interferon-inducible cell-autonomous immunity to cytosolic bacterial pathogens | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01AI108834 | GBPs in inflammasome activation and host defense to infection | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 4 | 2025 |
| R01GM107285 | Mechanism and Role of Membrane Fusion by the Atlastin GTPase | 4 | 2025 |
| T32HL007185 | Multidisciplinary Training Program in Lung Disease | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 4 | 2025 |
1 to 10 of 1,419Source NIH's project files
See all 1,419 nih grantsPapers1,970
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins. | J Microsc Ultrastruct | 2026 | 42824931 | PubTator, text mining | PubMed |
| Gestational week 13 - a critical window for pre-eclampsia pathogenesis: A cell-free RNA gene expression study. | Placenta | 2026 | 42762647 | PubTator, text mining | PubMed |
| Gut Dysbiosis Promotes Myocardial Hypertrophy via GBP2b/GBP1 in Chronic Colitis. | Circ Res | 2026 | 42677470 | PubTator, text mining | PubMed |
| Interferon-stimulated gene signature predicts clinical response to low-dose IL-2 in immune-mediated inflammatory diseases. | Ann Rheum Dis | 2026 | 42618420 | PubTator, text mining | PubMed |
| Redistribution of peripheral blood immune cell subsets and remodeling of intercellular communication in rare Behçet's disease: a single-cell transcriptomics study. | Front Med (Lausanne) | 2026 | 42614187 | PubTator, text mining | PubMed |
| Network-guided transcriptomics identifies drug-linked host-response biomarkers in tuberculosis disease-state transition. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42576022 | PubTator, text mining | PubMed |
| Melissa officinalis extract selectively suppresses STAT1 signaling in oral epithelial cells. | Front Immunol | 2026 | 42540501 | PubTator, text mining | PubMed |
| Multiparametric flow cytometry immune profiling of pulmonary and extra-pulmonary tuberculosis reveals distinct blood-based biomarker signatures. | Tuberculosis (Edinb) | 2026 | 42501466 | PubTator, text mining | PubMed |
| The Airway Transcriptome in Type 2 Cytokine Biomarker-High and -Low Severe Asthma. | Allergy | 2026 | 42473711 | PubTator, text mining | PubMed |
| Tumor microenvironment-oriented HNGCIscore identifies immunotherapy-sensitive subgroups in ICI retreatment of HER2-negative advanced gastric cancer. | Front Oncol | 2026 | 42459296 | PubTator, text mining | PubMed |
1 to 10 of 1,970
See all 1,970 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2633
GET https://conductscience.org/api/genes/v1/2633/patents