ConductScience.org, home

Gene · 26353

HSPB8: heat shock protein family B (small) member 8

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. HSPB8: heat shock protein family B (small) member 8. Genes, record 26353. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26353

On this page

Gene

Symbol
HSPB8
HGNC
Name
heat shock protein family B (small) member 8
HGNC
NCBI Gene ID
26353
NCBI Gene
HGNC ID
HGNC:30171
HGNC
Ensembl
ENSG00000152137
NCBI Gene
Aliases
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HMND2, HSP22, HSPB8-N1, HSPB8-N2, MFM13
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UJY1Heat shock protein beta-81961Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4762184 A22026-06-24108Q9UJY1Espacenet
EP 4762184 A22026-06-2425Q9UJY1Espacenet
EP 4762184 A22026-06-24311Q9UJY1Espacenet
EP 4762184 A22026-06-24333Q9UJY1Espacenet
EP 4762184 A22026-06-24409Q9UJY1Espacenet
JP 2026004568 A2026-01-1448716Q9UJY1Espacenet
EP 4650780 A22025-11-193140Q9UJY1Espacenet
JP 2025517970 A2025-06-123140Q9UJY1Espacenet
US 11446398 B22022-09-2037302Q9UJY1Espacenet
JP 2022524081 A2022-04-27140273Q9UJY1Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants723

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHSPB8 papersNewest fiscal year
P30MH092177Comprehensive NeuroHIV Center42025
R01NS059690Molecular Chaperones and Small Molecules42025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures42025
K24AR073317Clinical and Translational studies in muscle disease32025
P30CA091842Cancer Center Support Grant32025
P30EY005722Center Core Grant for Vision Research32025
R01AR068797Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models32025
P30CA013696Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025
P30CA077598Cancer Center Support Grant22025

1 to 10 of 723Source NIH's project files

See all 723 nih grants

Papers1,425

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
BAG3 coordinates astrocytic proteostasis of Alzheimer's disease-linked proteins via proteasome, autophagy, and retromer interactions.Proc Natl Acad Sci U S A202642804638PubTator, text miningPubMed
Chaperone-assisted selective autophagy (CASA) in polyglutamine-related diseases: From mechanisms to therapeutic perspectives.J Huntingtons Dis202642690709PubTator, text miningPubMed
Electric muscle stimulation attenuates neuroinflammation and improves the outcome of acute ischemic stroke in mice.Neurotherapeutics202642229070PubTator, text miningPubMed
Molecular, cellular, and clinical aspects of myofibrillar myopathy caused by HSPB8 frameshift mutations.Biochim Biophys Acta Mol Basis Dis202641951012PubTator, text miningPubMed
Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies.Front Cell Neurosci202641788195PubTator, text miningPubMed
Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential.Front Aging Neurosci202641767843PubTator, text miningPubMed
Obesity-linked genes may promote prostate cancer among Asian and Hispanic immigrants to North America.Front Public Health202641737617PubTator, text miningPubMed
Genetic Spectrum and Phenotypic Variability in Chinese Patients with Multisystem Proteinopathy and Related Disorders.Degener Neurol Neuromuscul Dis202641737544PubTator, text miningPubMed
Linking Oxidative Stress to Placental Dysfunction: The Key Role of Mitochondria in Trophoblast Function.Med Sci (Basel)202641718100PubTator, text miningPubMed
C-Terminal Fragment of Filamin C Containing Immunoglobulin-Like Domains 19-24 Selectively Interacts with the Small Heat Shock Protein HspB7.Biochemistry (Mosc)202641702738PubTator, text miningPubMed

1 to 10 of 1,425

See all 1,425 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/26353

GET https://conductscience.org/api/genes/v1/26353/patents?page=2