ConductScience.org, home
GCH1: GTP cyclohydrolase 1
API referenceFor AI assistants

Gene · 2643

Papers2,670

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,670

Download this page as JSON
TitleJournalYearPMIDFound bySource
Integrated network toxicology, machine learning, and multi-omics characterization of 2,4-DTBP neurotoxicity.Chem Biol Interact202642822756PubTator, text miningPubMed
Longxue tongluo capsule enhances ischemic stroke recovery via microbiota-metabolite-gene interactions.Metab Brain Dis202642804018PubTator, text miningPubMed
Predicted deficiency of the GTP cyclohydrolase I feedback regulatory protein (GFRP): a disorder of dynamic tetrahydrobiopterin homeostasis.Mol Genet Metab202642800280PubTator, text miningPubMed
Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges.Pharmacol Rep202642789241PubTator, text miningPubMed
FTO/m6A Regulate Prenatal Nicotine-Induced eNOS Uncoupling and BP Susceptibility.Hypertension202642779519PubTator, text miningPubMed
Correction to: Metabolic adaptations of inflammatory macrophages govern ferroptosis susceptibility via the GCH1-BH4-iNOS axis.J Immunol202642763889PubTator, text miningPubMed
Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review).Mol Med Rep202642757463PubTator, text miningPubMed
GCH1, identified by a ferroptosis-related prognostic model, contributes to progression and drug resistance of esophageal cancer.Chin J Cancer Res202642713103PubTator, text miningPubMed
The redox paradox in neurological disorders: balancing cytoprotection, ferroptosis, and therapeutic targeting.Brain Res202642700879PubTator, text miningPubMed
Association between circulating GTP cyclohydrolase 1 concentrations and acute ischemic stroke: an exploratory case-control study in a Chinese population.Front Neurol202642682434PubTator, text miningPubMed
[Genetic Dystonias].Medicina (B Aires)202642659549PubTator, text miningPubMed
Ferroptosis in Anthracycline Cardiotoxicity: Mechanisms, the Cardioprotection Paradox and the Limits of Single-Pathway Thinking.J Appl Toxicol202642608157PubTator, text miningPubMed
Comprehensive bioinformatic analyses identify a PANoptosome-related gene diagnostic signature in keloid fibroblasts.Burns202642607510PubTator, text miningPubMed
Hypoxic eNOS uncoupling as a consequence of DHFR downregulation in various human endothelial cell lines: the crucial role of the BH4 regeneration pathway.Am J Physiol Cell Physiol202642566752PubTator, text miningPubMed
Metabolic control of ferroptosis in cancer: lipid dependencies as therapeutic vulnerabilities.Front Oncol202642564157PubTator, text miningPubMed
Metabolic Profiling of Circulating and Tumour-Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients.Immunology202642552605PubTator, text miningPubMed
5-ALA Photodynamic Therapy Induces Competing Death and Survival Pathways in Glioblastoma Cells.Curr Issues Mol Biol202642510929PubTator, text miningPubMed
Molecular Effects of Indocyanine Green-Photodynamic Therapy on Programmed Cell Death Pathways in T98G and U-118MG Glioblastoma Cells-An RT-qPCR Study.Curr Issues Mol Biol202642510900PubTator, text miningPubMed
Ferroptosis Resistance: Redundant Antioxidant Networks Are a Barrier to Cancer Therapy.Antioxidants (Basel)202642510591PubTator, text miningPubMed
Statement of Retraction. Shuangxi Wang, Jian Xu, Ping Song, Benoit Viollet, and Ming-Hui Zou. In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I. Diabetes 2009;58:1893-1901. DOI: 10.2337/db09-0267. PMID: 19528375. PMCID: PMC2712774.
Diabetes202642475543PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Next page

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/genes/v1/2643/papers

API referenceFor AI assistants