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KAT2A: lysine acetyltransferase 2A
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Gene · 2648

Papers3,420

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,420

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TitleJournalYearPMIDFound bySource
Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy.Cancer Med202642768738PubTator, text miningPubMed
Structure-guided identification and experimental validation of NAT10-targeting small molecules in colorectal cancer cells.J Comput Aided Mol Des202642742862PubTator, text miningPubMed
MMSDH facilitates ACSL4 propionylation to counteract ferroptosis upon hypoxia and impairs PDAC chemotherapy efficacy.Nat Cancer202642728394PubTator, text miningPubMed
DHA Targets RAB1B to Mediate the Driving Force Transmission of Copper Ion Vesicular Endocytosis Under Copper Overload for Promoting Cuproptosis and Ferroptosis in Hepatic Stellate Cells.Int J Biol Sci202642694667PubTator, text miningPubMed
Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart.J Precis Med (Amst)202642644057PubTator, text miningPubMed
Structural plasticity drives convergent evolution and functional diversification of GNAT polyamine acetyltransferases.Structure202642636798PubTator, text miningPubMed
Pharmacological targeting of GCN5/PCAF (KAT2A/B): current drug discovery strategies and translational potential.Drug Discov Today202642624285PubTator, text miningPubMed
The KAT2/HDACⅡa-PGK-ALDO axis constitutes a dual degradation inhibition cascade links energy stress to glycolytic amplification.Proc Natl Acad Sci U S A202642611992PubTator, text miningPubMed
Top-Down Sequencing of Intact Proteoforms Using the timsOmni Mass Spectrometer: Accurate Determination of Co-Occurring Histone Modifications.Mol Cell Proteomics202642607871PubTator, text miningPubMed
The GCN5L2-SIX1 complex drives glycolysis to promote progression of triple-negative breast cancer.Cancer Lett202642601012PubTator, text miningPubMed
Crotonylation of ACAT1 K181 contributes to radioresistance by impacting lactate metabolism.Commun Biol202642587030PubTator, text miningPubMed
Beyond acetylation: Evaluating the emerging biology of lysine acylation.Cell Chem Biol202642586062PubTator, text miningPubMed
Disrupting a Convergent Acetylation Circuit Collapses Leukemic Identity Across AML Subtypes.bioRxiv202642523331PubTator, text miningPubMed
Histone acetyltransferases as integrative epigenetic regulators of plant abiotic stress responses.Plant Cell Rep202642463562PubTator, text miningPubMed
Integrative multi-omics analysis identifies histone methyltransferase SUV420H2 as a prognostic biomarker in clear cell renal cell carcinoma.Discov Oncol202642449034PubTator, text miningPubMed
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues.Science202642424456PubTator, text miningPubMed
USP22 is a novel vulnerability regulating MEIS1 protein abundance and gene transcription in KMT2Ar acute leukemia.Blood202642418681PubTator, text miningPubMed
A succinylation-based classifier predicts chemotherapy response in prostate cancer and reveals KAT2A as a therapeutic target.Clin Transl Med202642415249PubTator, text miningPubMed
GCN5 and TADA2B constitutively regulate XRCC1 function during DNA repair to maintain cell survival.Cell Death Differ202642399641PubTator, text miningPubMed
Revisiting retinoic acid in AML therapy: mechanisms of action and rational combination strategies.Br J Cancer202642393459PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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