Gene · 2648
KAT2A: lysine acetyltransferase 2A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KAT2A: lysine acetyltransferase 2A. Genes, record 2648. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2648
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q92830 | Histone acetyltransferase KAT2A | 837 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50515 | Q92830 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 649 | Q92830 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 450 | Q92830 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 450 | Q92830 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 649 | Q92830 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 42398 | Q92830 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 145369 | Q92830 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 5693 | Q92830 | Espacenet |
| US 11034647 B2 | 2021-06-15 | 5 | Q92830 | Espacenet |
| KR 1020210060362 A | 2021-05-26 | 1 | Q92830 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,312
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KAT2A papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 34 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 18 | 2025 |
| ZIABC011488 | Targeting Cancer Through Modifications and Metabolism | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 10 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 7 | 2025 |
| R35GM118068 | Transcription regulation in chromatin | 7 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 6 | 2025 |
| R35GM118090 | Molecular Mechanisms, Pathways and Inhibition of Acetyl-Transfer Reactions | 6 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 5 | 2025 |
1 to 10 of 2,312Source NIH's project files
See all 2,312 nih grantsPapers3,420
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy. | Cancer Med | 2026 | 42768738 | PubTator, text mining | PubMed |
| Structure-guided identification and experimental validation of NAT10-targeting small molecules in colorectal cancer cells. | J Comput Aided Mol Des | 2026 | 42742862 | PubTator, text mining | PubMed |
| MMSDH facilitates ACSL4 propionylation to counteract ferroptosis upon hypoxia and impairs PDAC chemotherapy efficacy. | Nat Cancer | 2026 | 42728394 | PubTator, text mining | PubMed |
| DHA Targets RAB1B to Mediate the Driving Force Transmission of Copper Ion Vesicular Endocytosis Under Copper Overload for Promoting Cuproptosis and Ferroptosis in Hepatic Stellate Cells. | Int J Biol Sci | 2026 | 42694667 | PubTator, text mining | PubMed |
| Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart. | J Precis Med (Amst) | 2026 | 42644057 | PubTator, text mining | PubMed |
| Structural plasticity drives convergent evolution and functional diversification of GNAT polyamine acetyltransferases. | Structure | 2026 | 42636798 | PubTator, text mining | PubMed |
| Pharmacological targeting of GCN5/PCAF (KAT2A/B): current drug discovery strategies and translational potential. | Drug Discov Today | 2026 | 42624285 | PubTator, text mining | PubMed |
| The KAT2/HDACⅡa-PGK-ALDO axis constitutes a dual degradation inhibition cascade links energy stress to glycolytic amplification. | Proc Natl Acad Sci U S A | 2026 | 42611992 | PubTator, text mining | PubMed |
| Top-Down Sequencing of Intact Proteoforms Using the timsOmni Mass Spectrometer: Accurate Determination of Co-Occurring Histone Modifications. | Mol Cell Proteomics | 2026 | 42607871 | PubTator, text mining | PubMed |
| The GCN5L2-SIX1 complex drives glycolysis to promote progression of triple-negative breast cancer. | Cancer Lett | 2026 | 42601012 | PubTator, text mining | PubMed |
1 to 10 of 3,420
See all 3,420 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2648
GET https://conductscience.org/api/genes/v1/2648/patents?page=2