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Gene · 26523

AGO1: argonaute RISC component 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AGO1: argonaute RISC component 1. Genes, record 26523. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26523

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Gene

Symbol
AGO1
HGNC
Name
argonaute RISC component 1
HGNC
NCBI Gene ID
26523
NCBI Gene
HGNC ID
HGNC:3262
HGNC
Ensembl
ENSG00000092847
NCBI Gene
Aliases
EIF2C, EIF2C1, GERP95, NEDLBAS, Q99, hAGO1, hAgo1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UL18Protein argonaute-18578Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445480Q9UL18Espacenet
EP 4650780 A22025-11-199268Q9UL18Espacenet
JP 2025517970 A2025-06-129268Q9UL18Espacenet
JP 2025062604 A2025-04-146264Q9UL18Espacenet
EP 4373845 A22024-05-2920Q9UL18Espacenet
JP 2024515999 A2024-04-1160Q9UL18Espacenet
US 11446398 B22022-09-206264Q9UL18Espacenet
JP 2022524081 A2022-04-27109235Q9UL18Espacenet
WO 2019222036 A12019-11-219Q9UL18Espacenet
JP 2019054813 A2019-04-11225915Q9UL18Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,448

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAGO1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
R01GM083300Selective regulatory and biogenesis mechanisms for microRNAs152025
R35GM118103Recognition of Cellular Targets by single and double-stranded nucleic acids92025
P30CA016672Cancer Center Support Grant72025
R01GM124320Target specificity of human RNA-induced silencing complex62025
P30CA014051Cancer Center Support (Core) Grant52025
P30CA033572Cancer Center Support Grant52025
P30CA045508CSHL Cancer Center Support Grant52025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center52025
R01GM138997Structural and molecular basis for cityRNA (cleavage-inducing tiny RNA)-directed RNA cleavage by AGO352025

1 to 10 of 1,448Source NIH's project files

See all 1,448 nih grants

Papers2,697

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Leishmania exosomal tRNA-derived small non-coding RNA fragments modulate host THP-1 derived macrophage proteins: A quantitative proteomic analysis.PLoS One202642616765PubTator, text miningPubMed
Two Japanese Cases Highlighting Structural and Phenotypic Overlap in AGO1- and AGO2-Related Neurodevelopmental Disorders.Clin Genet202642580685PubTator, text miningPubMed
Trans-species microRNAs from the parasitic plant Cuscuta campestris specifically avoid loading onto self Argonautes.Nucleic Acids Res202642417192PubTator, text miningPubMed
MicroRNA Biogenesis Pathway Gene Variants Are Associated with Prostate Cancer Susceptibility.Int J Mol Sci202642353292PubTator, text miningPubMed
Quenching the thirst internally: separating miRNA from target mRNA by condensation of AGO1.Plant Cell202642275594PubTator, text miningPubMed
Structural basis for RISC assembly of human Argonaute2.Mol Cell202642190652PubTator, text miningPubMed
miRNA-Processing Gene Variants and Neuroblastoma Susceptibility: A Pilot Case-Control Study.Cureus202641982370PubTator, text miningPubMed
Association between polymorphisms in microRNA biosynthesis genes and acute lymphoblastic leukemia susceptibility in Chinese children and adolescents.Per Med202641923653PubTator, text miningPubMed
Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response.Allergy Asthma Immunol Res202641914533PubTator, text miningPubMed
Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide.Sci Adv202641894501PubTator, text miningPubMed

1 to 10 of 2,697

See all 2,697 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/26523

GET https://conductscience.org/api/genes/v1/26523/patents?page=2