Gene · 26523
AGO1: argonaute RISC component 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. AGO1: argonaute RISC component 1. Genes, record 26523. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/26523
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UL18 | Protein argonaute-1 | 857 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45480 | Q9UL18 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9268 | Q9UL18 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9268 | Q9UL18 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 6264 | Q9UL18 | Espacenet |
| EP 4373845 A2 | 2024-05-29 | 20 | Q9UL18 | Espacenet |
| JP 2024515999 A | 2024-04-11 | 60 | Q9UL18 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 6264 | Q9UL18 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 109235 | Q9UL18 | Espacenet |
| WO 2019222036 A1 | 2019-11-21 | 9 | Q9UL18 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 225915 | Q9UL18 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,448
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | AGO1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| R01GM083300 | Selective regulatory and biogenesis mechanisms for microRNAs | 15 | 2025 |
| R35GM118103 | Recognition of Cellular Targets by single and double-stranded nucleic acids | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R01GM124320 | Target specificity of human RNA-induced silencing complex | 6 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 5 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 5 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 5 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 5 | 2025 |
| R01GM138997 | Structural and molecular basis for cityRNA (cleavage-inducing tiny RNA)-directed RNA cleavage by AGO3 | 5 | 2025 |
1 to 10 of 1,448Source NIH's project files
See all 1,448 nih grantsPapers2,697
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Leishmania exosomal tRNA-derived small non-coding RNA fragments modulate host THP-1 derived macrophage proteins: A quantitative proteomic analysis. | PLoS One | 2026 | 42616765 | PubTator, text mining | PubMed |
| Two Japanese Cases Highlighting Structural and Phenotypic Overlap in AGO1- and AGO2-Related Neurodevelopmental Disorders. | Clin Genet | 2026 | 42580685 | PubTator, text mining | PubMed |
| Trans-species microRNAs from the parasitic plant Cuscuta campestris specifically avoid loading onto self Argonautes. | Nucleic Acids Res | 2026 | 42417192 | PubTator, text mining | PubMed |
| MicroRNA Biogenesis Pathway Gene Variants Are Associated with Prostate Cancer Susceptibility. | Int J Mol Sci | 2026 | 42353292 | PubTator, text mining | PubMed |
| Quenching the thirst internally: separating miRNA from target mRNA by condensation of AGO1. | Plant Cell | 2026 | 42275594 | PubTator, text mining | PubMed |
| Structural basis for RISC assembly of human Argonaute2. | Mol Cell | 2026 | 42190652 | PubTator, text mining | PubMed |
| miRNA-Processing Gene Variants and Neuroblastoma Susceptibility: A Pilot Case-Control Study. | Cureus | 2026 | 41982370 | PubTator, text mining | PubMed |
| Association between polymorphisms in microRNA biosynthesis genes and acute lymphoblastic leukemia susceptibility in Chinese children and adolescents. | Per Med | 2026 | 41923653 | PubTator, text mining | PubMed |
| Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response. | Allergy Asthma Immunol Res | 2026 | 41914533 | PubTator, text mining | PubMed |
| Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide. | Sci Adv | 2026 | 41894501 | PubTator, text mining | PubMed |
1 to 10 of 2,697
See all 2,697 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/26523
GET https://conductscience.org/api/genes/v1/26523/patents?page=2