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Gene · 2661

GDF9: growth differentiation factor 9

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GDF9: growth differentiation factor 9. Genes, record 2661. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2661

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Gene

Symbol
GDF9
HGNC
Name
growth differentiation factor 9
HGNC
NCBI Gene ID
2661
NCBI Gene
HGNC ID
HGNC:4224
HGNC
Ensembl
ENSG00000164404
NCBI Gene
Aliases
POF14
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60383Growth/differentiation factor 94540Ensembl, GeneID, HGNC

Source UniProt

Patents69

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910070O60383Espacenet
JP 2025147176 A2025-10-065860O60383Espacenet
JP 2025138725 A2025-09-252020O60383Espacenet
JP 2025138725 A2025-09-252538O60383Espacenet
JP 2025529142 A2025-09-046479O60383Espacenet
US 12371689 B22025-07-296479O60383Espacenet
JP 2025517970 A2025-06-1210070O60383Espacenet
US 12280021 B22025-04-2281O60383Espacenet
US 12269793 B22025-04-0881O60383Espacenet
JP 2025028160 A2025-02-285860O60383Espacenet

1 to 10 of 69

See all 69 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants403

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGDF9 papersNewest fiscal year
R01HD032067Transforming growth factor β family signaling pathways in ovarian and uterine biology62025
K12HD000849Reproductive Scientist Development Program42025
P51OD011092Support for National Primate Research Center32025
P30CA008748Cancer Center Support Grant22025
P30CA054174Mays Cancer Center at UT Health SA22025
P30ES019776HERCULES: Exposome Research Center22025
P51OD011106Wisconsin National Primate Research Center Support22025
P51OD011133The Southwest National Primate Research Center22025
R01HD082208Anti-Mullerian Hormone Actions to Control Primate Folliculogenesis22025
T32HD007203Training in Reproductive Sciences22025

1 to 10 of 403Source NIH's project files

See all 403 nih grants

Papers1,429

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Urinary and Recombinant Follicle-Stimulating Hormone in Supporting Primate Follicular Development In Vitro.Curr Issues Mol Biol202642793228PubTator, text miningPubMed
MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism.Elife202642765984PubTator, text miningPubMed
Innovative Xenotransplantation of Reconstructed Human Artificial Ovary Using 3D-Printed Scaffolds and Umbilical Cord Mesenchymal Stem Cells.Int J Fertil Steril202642703805PubTator, text miningPubMed
Proprotein convertase activity regulates cumulus-oocyte-complex matrix integrity and cumulus cell migration during ovulation via a GDF9-dependent mechanism.bioRxiv202642539241PubTator, text miningPubMed
Ovarian Function, Hormonal, Metabolic, Oxidative Stress, and Gene Expression Biomarker Responses of Holstein Heifers Under Heat Stress Conditions to a Reduced Dose of Nanofabricated GnRH Analog Within the Ovsynch Protocol.
Animals (Basel)202642511042PubTator, text miningPubMed
Gamete co-incubation duration modulates blastocyst developmental competence in buffalo through regulation of growth factors, steroidogenesis and oxidative stress pathways.Mol Biol Rep202642489973PubTator, text miningPubMed
Regulation of ovarian function in domestic animals: translational insights into human ovarian dynamics and dysfunction.Front Endocrinol (Lausanne)202642483683PubTator, text miningPubMed
Ovarian function and X chromosome tissue mosaicism in adolescents with Turner syndrome and ongoing spontaneous puberty.Front Endocrinol (Lausanne)202642483667PubTator, text miningPubMed
Developmental and functional landscape of theca cells in ovarian biology.Biol Res202642260579PubTator, text miningPubMed
Insights into Copy Number Variation Architecture in Black Bengal Goat Genome.Int J Mol Sci202642123621PubTator, text miningPubMed

1 to 10 of 1,429

See all 1,429 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2661

GET https://conductscience.org/api/genes/v1/2661/patents?page=2