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Gene · 2662

GDF10: growth differentiation factor 10

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GDF10: growth differentiation factor 10. Genes, record 2662. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2662

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Gene

Symbol
GDF10
HGNC
Name
growth differentiation factor 10
HGNC
NCBI Gene ID
2662
NCBI Gene
HGNC ID
HGNC:4215
HGNC
Ensembl
ENSG00000266524
NCBI Gene
Aliases
BIP, BMP-3b, BMP3B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P55107Growth/differentiation factor 104780Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-065846P55107Espacenet
JP 2025138725 A2025-09-251854P55107Espacenet
JP 2025529142 A2025-09-046471P55107Espacenet
US 12371689 B22025-07-296471P55107Espacenet
JP 2025032204 A2025-03-1128940P55107Espacenet
JP 2025028160 A2025-02-285846P55107Espacenet
KR 1020250010750 A2025-01-215846P55107Espacenet
EP 4461818 A22024-11-1328940P55107Espacenet
JP 2024109657 A2024-08-145853P55107Espacenet
JP 2023145599 A2023-10-111854P55107Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,004

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGDF10 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA030199Cancer Center Support Grant (CCSG)72025
P30DK034854Integrated Epithelial and Muscosal Biology72025
P30CA013330Cancer Center Support Grant62025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA047904Cancer Center Support Grant52025
P30CA016058Cancer Center Support Grant42025
P30CA054174Mays Cancer Center at UT Health SA42025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)42025

1 to 10 of 2,004Source NIH's project files

See all 2,004 nih grants

Papers2,641

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ER Stress Regulates HIV Tat and Alcohol-Induced NLRP6 Activation in Astrocytes.CNS Neurosci Ther202642806587PubTator, text miningPubMed
Neuroprotective Effects of Two N-Benzylamides in Models of Oxidative Stress, Neurite Outgrowth and Neurodegeneration.Oxid Med Cell Longev202642751784PubTator, text miningPubMed
p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma.Nat Commun202642686683PubTator, text miningPubMed
TMEM97 links endoplasmic reticulum stress to hepatic stellate cell activation in experimental liver fibrosis: pharmacological attenuation by CT1812.Eur J Pharmacol202642617904PubTator, text miningPubMed
CNTN-1 regulates malignant biological behaviors of lung squamous cell carcinoma (LUSC) via the endoplasmic reticulum stress (ERS)/epithelial-mesenchymal transition (EMT) axis.Transl Cancer Res202642445425PubTator, text miningPubMed
Kefir peptides attenuate intestinal injury induced by combined exposure to microplastics and particulate matter.Ecotoxicol Environ Saf202642320376PubTator, text miningPubMed
FAP-intrinsic Hedgehog signaling controls intramuscular adipogenesis, fibrosis, and myofiber regeneration.bioRxiv202642282532PubTator, text miningPubMed
Celastrol induces apoptosis of myelodysplastic syndrome cells through a ROS-dependent pro-apoptotic endoplasmic-reticulum stress pathway.Cancer Cell Int202642231363PubTator, text miningPubMed
GDF10 attenuates chondral fibrosis and cartilage degeneration in osteonecrosis of the femoral head: Insight into underlying regulatory mechanisms.Osteoarthritis Cartilage202642176880PubTator, text miningPubMed
Ginsenoside Re Suppresses Tumorigenesis in NSCLC through PERK-Mediated Endoplasmic Reticulum Stress and the Mitochondrial Apoptosis Pathway.Curr Med Chem202642083370PubTator, text miningPubMed

1 to 10 of 2,641

See all 2,641 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2662

GET https://conductscience.org/api/genes/v1/2662/patents?page=2