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Gene · 2669

GEM: GTP binding protein overexpressed in skeletal muscle

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GEM: GTP binding protein overexpressed in skeletal muscle. Genes, record 2669. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2669

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Gene

Symbol
GEM
HGNC
Name
GTP binding protein overexpressed in skeletal muscle
HGNC
NCBI Gene ID
2669
NCBI Gene
HGNC ID
HGNC:4234
HGNC
Ensembl
ENSG00000164949
NCBI Gene
Aliases
KIR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P55040GTP-binding protein GEM2963Ensembl, GeneID, HGNC

Source UniProt

Patents63

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448386P55040Espacenet
JP 2026004568 A2026-01-1448387P55040Espacenet
EP 4650780 A22025-11-193838P55040Espacenet
EP 4641201 A22025-10-293401P55040Espacenet
JP 2025147176 A2025-10-0614651P55040Espacenet
JP 2025517969 A2025-06-123401P55040Espacenet
JP 2025517970 A2025-06-123838P55040Espacenet
JP 2025032204 A2025-03-1128954P55040Espacenet
JP 2025032204 A2025-03-1128955P55040Espacenet
JP 2025028160 A2025-02-2814651P55040Espacenet

1 to 10 of 63

See all 63 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,708

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGEM papersNewest fiscal year
P30CA008748Cancer Center Support Grant172025
P30CA016672Cancer Center Support Grant82025
P30ES010126UNC Center for Environmental Health and Susceptibility72025
P30CA016086Cancer Center Support Grant62025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA091842Cancer Center Support Grant52025
P30DK036836Diabetes Research Center52025
R01NS028840Mitogenic Activities in Neurofibromatosis52025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant42025
P30CA015704Cancer Center Support Grant42025

1 to 10 of 1,708Source NIH's project files

See all 1,708 nih grants

Papers2,096

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Synthesis, Structure-Activity Studies, and Therapeutic Potential of Met-enkephalin Derivatives.Curr Top Med Chem202642725519PubTator, text miningPubMed
Improving the accuracy and generalizability of molecular property regression models with a substructure-substitution-rule-informed framework.Chem Sci202642375178PubTator, text miningPubMed
Cigarette Smoke-Induced Alveolar Macrophage Senescence via GEM/SIRT3-Mediated Mitochondrial Dysfunction.Adv Sci (Weinh)202642325089PubTator, text miningPubMed
Rare Variants in PFIC-Related Genes Among Adults With Intrahepatic Cholestasis.Hepatol Res202642322153PubTator, text miningPubMed
Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells.Nat Immunol202642230957PubTator, text miningPubMed
GEM-CAN: A real-world dataset of CAN-bus attack scenarios on an autonomous vehicle for intrusion-detection research.Data Brief202642205777PubTator, text miningPubMed
Genome instability triggers intercellular DNA transfer between human cells.Cell202642161273PubTator, text miningPubMed
An integrated single-cell and spatial proteotranscriptomics atlas of fibroblast-driven immunoregulation within the human adult oral cavity.Cell Press Blue202642147490PubTator, text miningPubMed
gMISpy: integration of complex regulatory networks and genome scale metabolic models.Bioinformatics202641965071PubTator, text miningPubMed
Human receptive endometrial assembloid for deciphering the implantation window.Elife202641920166PubTator, text miningPubMed

1 to 10 of 2,096

See all 2,096 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2669

GET https://conductscience.org/api/genes/v1/2669/patents?page=2