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GFI1: growth factor independent 1 transcriptional repressor
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Gene · 2672

Papers1,987

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,987

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TitleJournalYearPMIDFound bySource
Agonism of GPR84 Attenuates Free Fatty Acid-Induced Endothelial Inflammation and Monocyte Adhesion via Gfi1/NF-κB Pathway.Arq Bras Cardiol202642820599PubTator, text miningPubMed
Gambogic Acid Induces Apoptosis in Raji Lymphoma Cells Via Gfi-1/STAT5 Signaling.J Vis Exp202642644555PubTator, text miningPubMed
Macrophage-specific targeting of histone demethylases with small-molecule inhibitors suppresses inflammatory response in vivo.J Biol Chem202642409265PubTator, text miningPubMed
GFI1 enhances MHC-I expression in tumor cells and augments tumor responsiveness to PD-1/PD-L1 inhibitors.Cancer Immunol Immunother202642174278PubTator, text miningPubMed
The GFI1 Gene Family: Evolution, Structure, and Its Role in Immune Responses.J Mol Evol202642045596PubTator, text miningPubMed
The GFI1-FOXO1 axis regulates NK cell maturation and function.Nat Commun202642020400PubTator, text miningPubMed
Base-resolution DNA methylome of human MDS hematopoietic stem cell reveals TET2-GFI1 epigenetic axis repressing MDS.Immun Inflamm202641929356PubTator, text miningPubMed
Lineage-Specific Disruption of Hematopoiesis by Oxaliplatin: Mechanisms of Erythropoietin Resistance and Immune Suppression.J Hematol Oncol Res202641868970PubTator, text miningPubMed
Transcriptional programming governs the transition from shared progenitors to divergent CD8+ T cell fates.Immunol Cell Biol202641814649PubTator, text miningPubMed
An interpretable machine learning model for predicting prognosis of medulloblastoma integrating genetic and clinical features.Commun Med (Lond)202641807642PubTator, text miningPubMed
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities.MedComm (2020)202641799937PubTator, text miningPubMed
Genomic analysis of dental pulp mesenchymal stromal cells for therapeutic applications.Regen Ther202641777871PubTator, text miningPubMed
Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth.Epigenetics202641774615PubTator, text miningPubMed
Modeling pediatric brain tumors with human stem cells.Front Cell Neurosci202641757347PubTator, text miningPubMed
Mechanisms of HIV Latency in Hematopoietic Progenitors: GFI1 as a Key Regulator.bioRxiv202641756862PubTator, text miningPubMed
Phenotypic Variability Associated with Jagunal Homolog 1 (JAGN1) Deficiency Caused by the c.63G>T Variant.Int J Mol Sci202641751872PubTator, text miningPubMed
The Interleukin-7 Receptor Signaling Pathway and Its Perturbation in Immunodeficiency, Autoimmune Disease and Lymphoid Malignancy.Biomolecules202641750289PubTator, text miningPubMed
Inside the Battle Against Acute Myeloid Leukemia: Biology, Breakthroughs, and Hope.Cells202641744781PubTator, text miningPubMed
Metabolic checkpoints in the regulation of Th17 cells: implications for uveitis pathogenesis and therapy.Front Immunol202641743733PubTator, text miningPubMed
DNA methylation as a biomarker of prenatal exposures: current challenges and opportunities.Environ Epigenet202641736803PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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