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Gene · 2673

GFPT1: glutamine--fructose-6-phosphate transaminase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GFPT1: glutamine--fructose-6-phosphate transaminase 1. Genes, record 2673. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2673

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Gene

Symbol
GFPT1
HGNC
Name
glutamine--fructose-6-phosphate transaminase 1
HGNC
NCBI Gene ID
2673
NCBI Gene
HGNC ID
HGNC:4241
HGNC
Ensembl
ENSG00000198380
NCBI Gene
Aliases
CMS12, CMSTA1, GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q06210Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 169916Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21220Q06210Espacenet
JP 2025529142 A2025-09-041694Q06210Espacenet
US 12371689 B22025-07-291694Q06210Espacenet
WO 2024215987 A12024-10-1787Q06210Espacenet
WO 2024215989 A12024-10-1792Q06210Espacenet
JP 2024536859 A2024-10-0868Q06210Espacenet
KR 1020240069799 A2024-05-2068Q06210Espacenet
JP 2023521663 A2023-05-25219Q06210Espacenet
US 11564998 B22023-01-315925Q06210Espacenet
US 11446398 B22022-09-2035194Q06210Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,022

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGFPT1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant62025
ZIADK060103Enzymes of O-GlcNAc cycling linked to type-2 diabetes and neurodegeneration62025
ZIADK060101Targeted disruption the enzymes of O-GlcNAc cycling: Animal models of Disease52025
P01CA117969Genetics and Biology of Pancreatic Ductal Adenocarcinoma42025
P30CA015704Cancer Center Support Grant32025
R01DK099551New Congenital Disorders of Glycosylation: Therapy and Models32025
R01GM125939Chemical Tools for the Investigation and Manipulation of Protein Glycosylation32025
UL1TR002373University of Wisconsin Institute for Clinical and Translational Research32025
ZIADK060102Calmodulin-driven Nuclear Trafficking linked to diabetes and insulin signaling32025

1 to 10 of 1,022Source NIH's project files

See all 1,022 nih grants

Papers1,425

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations.Cell Rep202642726641PubTator, text miningPubMed
Gfpt2 modulates fibroblast activation by glutathione metabolism.J Mol Cell Cardiol202642586235PubTator, text miningPubMed
miR-335-3p acts as a tumor suppressor in esophageal squamous cell carcinoma and predicts favorable prognosis.Hereditas202642482156PubTator, text miningPubMed
SMR Analysis Integrating GWAS and eQTL Data Reveals UHRF1BP1 and SNRPC as Potential Drug Targets for Low Back Pain.J Pain Res202642454014PubTator, text miningPubMed
Integrated Proteomic and Metabolomic Analyses Characterise Molecular Alterations Associated with JSRV-Induced OPA.Biology (Basel)202642450530PubTator, text miningPubMed
Plasma Proteomic Changes in GRN and C9orf72 Frontotemporal Dementia.Eur J Neurol202642438357PubTator, text miningPubMed
Integrative statistical genetics prioritizes candidate ASCVD susceptibility genes across tissues.Mol Med202642402552PubTator, text miningPubMed
CSF1R regulates monocyte subset differentiation and intracellular metabolism.Nat Commun202642401537PubTator, text miningPubMed
Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1.Muscle Nerve202642387671PubTator, text miningPubMed
Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis.Biomedicines202642351616PubTator, text miningPubMed

1 to 10 of 1,425

See all 1,425 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2673

GET https://conductscience.org/api/genes/v1/2673/patents?page=2