Gene · 2673
GFPT1: glutamine--fructose-6-phosphate transaminase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GFPT1: glutamine--fructose-6-phosphate transaminase 1. Genes, record 2673. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2673
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q06210 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 699 | 16 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 220 | Q06210 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1694 | Q06210 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1694 | Q06210 | Espacenet |
| WO 2024215987 A1 | 2024-10-17 | 87 | Q06210 | Espacenet |
| WO 2024215989 A1 | 2024-10-17 | 92 | Q06210 | Espacenet |
| JP 2024536859 A | 2024-10-08 | 68 | Q06210 | Espacenet |
| KR 1020240069799 A | 2024-05-20 | 68 | Q06210 | Espacenet |
| JP 2023521663 A | 2023-05-25 | 219 | Q06210 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 5925 | Q06210 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 35194 | Q06210 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,022
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GFPT1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| ZIADK060103 | Enzymes of O-GlcNAc cycling linked to type-2 diabetes and neurodegeneration | 6 | 2025 |
| ZIADK060101 | Targeted disruption the enzymes of O-GlcNAc cycling: Animal models of Disease | 5 | 2025 |
| P01CA117969 | Genetics and Biology of Pancreatic Ductal Adenocarcinoma | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| R01DK099551 | New Congenital Disorders of Glycosylation: Therapy and Models | 3 | 2025 |
| R01GM125939 | Chemical Tools for the Investigation and Manipulation of Protein Glycosylation | 3 | 2025 |
| UL1TR002373 | University of Wisconsin Institute for Clinical and Translational Research | 3 | 2025 |
| ZIADK060102 | Calmodulin-driven Nuclear Trafficking linked to diabetes and insulin signaling | 3 | 2025 |
1 to 10 of 1,022Source NIH's project files
See all 1,022 nih grantsPapers1,425
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations. | Cell Rep | 2026 | 42726641 | PubTator, text mining | PubMed |
| Gfpt2 modulates fibroblast activation by glutathione metabolism. | J Mol Cell Cardiol | 2026 | 42586235 | PubTator, text mining | PubMed |
| miR-335-3p acts as a tumor suppressor in esophageal squamous cell carcinoma and predicts favorable prognosis. | Hereditas | 2026 | 42482156 | PubTator, text mining | PubMed |
| SMR Analysis Integrating GWAS and eQTL Data Reveals UHRF1BP1 and SNRPC as Potential Drug Targets for Low Back Pain. | J Pain Res | 2026 | 42454014 | PubTator, text mining | PubMed |
| Integrated Proteomic and Metabolomic Analyses Characterise Molecular Alterations Associated with JSRV-Induced OPA. | Biology (Basel) | 2026 | 42450530 | PubTator, text mining | PubMed |
| Plasma Proteomic Changes in GRN and C9orf72 Frontotemporal Dementia. | Eur J Neurol | 2026 | 42438357 | PubTator, text mining | PubMed |
| Integrative statistical genetics prioritizes candidate ASCVD susceptibility genes across tissues. | Mol Med | 2026 | 42402552 | PubTator, text mining | PubMed |
| CSF1R regulates monocyte subset differentiation and intracellular metabolism. | Nat Commun | 2026 | 42401537 | PubTator, text mining | PubMed |
| Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1. | Muscle Nerve | 2026 | 42387671 | PubTator, text mining | PubMed |
| Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis. | Biomedicines | 2026 | 42351616 | PubTator, text mining | PubMed |
1 to 10 of 1,425
See all 1,425 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2673
GET https://conductscience.org/api/genes/v1/2673/patents?page=2