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Gene · 2683

B4GALT1: beta-1,4-galactosyltransferase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. B4GALT1: beta-1,4-galactosyltransferase 1. Genes, record 2683. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2683

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Gene

Symbol
B4GALT1
HGNC
Name
beta-1,4-galactosyltransferase 1
HGNC
NCBI Gene ID
2683
NCBI Gene
HGNC ID
HGNC:924
HGNC
Ensembl
ENSG00000086062
NCBI Gene
Aliases
B4GAL-T1, CDG2D, CLDLFIB, GGTB2, GT1, GTB, beta4Gal-T1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15291Beta-1,4-galactosyltransferase 139819Ensembl, GeneID, HGNC

Source UniProt

Patents114

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4807367 A22026-09-1637P15291Espacenet
EP 4774376 A12026-07-155P15291Espacenet
JP 2026067851 A2026-04-21243P15291Espacenet
JP 2026067872 A2026-04-2143P15291Espacenet
JP 2026004568 A2026-01-1469151P15291Espacenet
JP 2025540146 A2025-12-112P15291Espacenet
EP 4641201 A22025-10-2910511P15291Espacenet
JP 2025530569 A2025-09-114P15291Espacenet
JP 2025529142 A2025-09-04559P15291Espacenet
KR 1020250115388 A2025-07-302P15291Espacenet

1 to 10 of 114

See all 114 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,018

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleB4GALT1 papersNewest fiscal year
R01GM083144Characterization of mammalian COG complex-interacting Golgi trafficking machinery122025
R01CA200423Chemical Glycoproteomics42025
P01HL151333Molecular and Clinical Glycobiology of the Bone Marrow Environment32025
P30CA008748Cancer Center Support Grant32025
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes32025
R01HL089224Carbohydrate-Mediated Platelet Clearance32025
R01HL103411Systems Biology of Glycosylation32025
R24GM137782National Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRC32025
R35GM119850Unraveling the mammalian secretory pathway through systems biology and algorithm development32025
UL1TR001881UCLA Clinical and Translational Science Institute32025

1 to 10 of 1,018Source NIH's project files

See all 1,018 nih grants

Papers1,884

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Glycosylation orchestrates megakaryocytic fate of hematopoietic stem cells via Wnt-MUC13 signaling.Nat Commun202642733053PubTator, text miningPubMed
Development and internal validation of a six-gene prognostic model based on galactose metabolism for overall survival in lung adenocarcinoma.Transl Cancer Res202642724461PubTator, text miningPubMed
B3GNT5-associated glycosylation remodeling in tumor-associated macrophages supports TGF-β-related glioma progression.Biochim Biophys Acta Gen Subj202642715804PubTator, text miningPubMed
Programmable HMO biosynthesis enabled by human cell-based glycoengineering.Glycobiology202642616032PubTator, text miningPubMed
B4GALT1-related congenital disorder of glycosylation mimicking Ehlers-Danlos syndrome: a child with multisystem involvement and nephrotic syndrome.Clin Exp Pediatr202642526876PubTator, text miningPubMed
Kaposi Sarcoma Herpes Virus Reprograms Mesenchymal Cell Glycosylation to control platelet-derived growth factor receptor A signaling.bioRxiv202642427740PubTator, text miningPubMed
Biocatalytic C3 β-O-Glycosylation of Triterpenes and Sterols to Synthesize Natural and Unnatural Saponins.J Am Chem Soc202642390099PubTator, text miningPubMed
Chemoenzymatic synthesis of unusual antibody glycoforms using E. coli expressed human and bovine β-1,4-galactosyltransferase and their mutants.Carbohydr Res202642378775PubTator, text miningPubMed
Biosynthesis of human milk oligosaccharides (HMOs) in glycoengineered human cells.Glycobiology202642324760PubTator, text miningPubMed
Reconstitution of human milk oligosaccharide biosynthesis in cultured mammalian cells.Metab Eng202642323078PubTator, text miningPubMed

1 to 10 of 1,884

See all 1,884 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2683

GET https://conductscience.org/api/genes/v1/2683/patents?page=2