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Gene · 2694

CBLIF: cobalamin binding intrinsic factor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CBLIF: cobalamin binding intrinsic factor. Genes, record 2694. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2694

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Gene

Symbol
CBLIF
HGNC
Name
cobalamin binding intrinsic factor
HGNC
NCBI Gene ID
2694
NCBI Gene
HGNC ID
HGNC:4268
HGNC
Ensembl
ENSG00000134812
NCBI Gene
Aliases
GIF, IF, IFMH, INF, TCN3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P27352Cobalamin binding intrinsic factor4172Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21320P27352Espacenet
JP 2026004568 A2026-01-1447389P27352Espacenet
EP 4650780 A22025-11-191625P27352Espacenet
JP 2025147176 A2025-10-065969P27352Espacenet
JP 2025529142 A2025-09-046495P27352Espacenet
US 12371689 B22025-07-296495P27352Espacenet
JP 2025517970 A2025-06-121625P27352Espacenet
JP 2025028160 A2025-02-285969P27352Espacenet
KR 1020250010750 A2025-01-215969P27352Espacenet
JP 2024109657 A2024-08-145976P27352Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants982

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCBLIF papersNewest fiscal year
P30DK052574Host-environment interactions in the pathophysiology of digestive disease192025
P30DK058404Molecular and Cellular Basis for Digestive Diseases192025
R01DK094989REGULATION OF ATROPHY-INDUCED PROGENITOR CELLS IN THE GASTRIC CORPUS162025
R01DK105129MECHANISMS OF CHIEF CELL DEDIFFERENTIATION162025
I01BX000930Oxyntic Atrophy and Novel Gastric Lineages.152025
R01DK101332Induction and Evolution of Metaplasia in the Stomach152025
P30CA068485Cancer Center Support Grant102025
P30CA016058Cancer Center Support Grant92025
P30CA091842Cancer Center Support Grant82025
P30DK056338Texas Medical Center Digestive Diseases Center62025

1 to 10 of 982Source NIH's project files

See all 982 nih grants

Papers3,464

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-crystal X-ray and in crystallo XANES studies resolve cobalt coordination in cobalamin and rule out radiation-induced ligand loss in human intrinsic factor.Acta Crystallogr D Struct Biol202642734119PubTator, text miningPubMed
A Length-Aware C-Terminal Rule for Prioritizing Short ACE-Inhibitory Peptides from Food Protein Hydrolysates.Foods202642588022PubTator, text miningPubMed
Distinct IgM and IgG autoantibody profiles characterize incomplete and classified systemic autoimmune diseases.Front Immunol202642389530PubTator, text miningPubMed
Yes-Associated Protein Drives Helicobacter pylori-Induced Metaplastic Changes in Gastric Epithelium.Cell Mol Gastroenterol Hepatol202642173319PubTator, text miningPubMed
Tff2 marks gastric corpus progenitors that give rise to pyloric metaplasia/SPEM following injury.Gut202641980762PubTator, text miningPubMed
Research Progress on Anticancer Mechanism of Ginsenoside Regulating Tumor Microenvironment.Curr Issues Mol Biol202641899480PubTator, text miningPubMed
The mouse gastric surface epithelial cell and its response to early Helicobacter pylori infection.Virulence202641824631PubTator, text miningPubMed
Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.Sci Adv202641811963PubTator, text miningPubMed
From concept to practice: real-world safety of JAK inhibitors in rheumatoid arthritis treatment.Front Med (Lausanne)202641767496PubTator, text miningPubMed
Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial® Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial.
Pharmaceutics202641754978PubTator, text miningPubMed

1 to 10 of 3,464

See all 3,464 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2694

GET https://conductscience.org/api/genes/v1/2694/patents?page=2