ConductScience.org, home

Library / Genes

GJA1: gap junction protein alpha 1

1 protein, 164 patents, 0 drugs, 0 trials, 6,947 NIH grants and 16,529 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGJA1HGNC
Namegap junction protein alpha 1HGNC
NCBI Gene ID2697NCBI Gene
HGNC IDHGNC:4274HGNC
EnsemblENSG00000152661NCBI Gene
AliasesAVSD3, CMDR, CX43, EKVP, EKVP3, GJAL, HLHS1, HSS, ODD, ODDD, ODOD, PPKCA, SDTY3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P17302Gap junction alpha-1 protein38219Ensembl, GeneID, HGNCUniProt

Patents 164

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026510343 A2026-04-02100P17302Espacenet
JP 2026049021 A2026-03-179P17302Espacenet
EP 4677087 A12026-01-14100P17302Espacenet
EP 4650780 A22025-11-193172P17302Espacenet
EP 4641201 A22025-10-292733P17302Espacenet
JP 2025163148 A2025-10-281P17302Espacenet
JP 2025529142 A2025-09-041712P17302Espacenet
JP 2025122152 A2025-08-209P17302Espacenet
US 12371689 B22025-07-291712P17302Espacenet
JP 2025517969 A2025-06-122733P17302Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6947

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01GM072631Mechanisms of Gap Junction Regulation342,025NIH's project files
R01EY012085Intercellular Communication in the Eye Lens332,025NIH's project files
P30CA016672Cancer Center Support Grant222,025NIH's project files
R01HL076485Engineering Vascularized Cardiac Muscle202,025NIH's project files
P42ES004911Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands152,025NIH's project files
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL152,025NIH's project files
R01GM099490Gating and Regulation of Connexin Hemichannels122,025NIH's project files
P30DK017047Diabetes Research Center112,025NIH's project files
P30DK063491Diabetes Research Center (DRC)112,025NIH's project files
P30EY008126Core Grant in Vision Research112,025NIH's project files

Papers 16529

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827426PubTator, text miningPubMed
42821487PubTator, text miningPubMed
42816417PubTator, text miningPubMed
42798645PubTator, text miningPubMed
42794472PubTator, text miningPubMed
42778872PubTator, text miningPubMed
42777083PubTator, text miningPubMed
42754538PubTator, text miningPubMed
42751622PubTator, text miningPubMed
42743660PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license