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Gene · 27022

FOXD3: forkhead box D3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FOXD3: forkhead box D3. Genes, record 27022. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27022

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Gene

Symbol
FOXD3
HGNC
Name
forkhead box D3
HGNC
NCBI Gene ID
27022
NCBI Gene
HGNC ID
HGNC:3804
HGNC
Ensembl
ENSG00000187140
NCBI Gene
Aliases
AIS1, Genesis, HFH2, VAMAS2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UJU5Forkhead box protein D34780Ensembl, GeneID, HGNC

Source UniProt

Patents19

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16620Q9UJU5Espacenet
JP 2026004568 A2026-01-1446532Q9UJU5Espacenet
JP 2025147176 A2025-10-0614982Q9UJU5Espacenet
JP 2025028160 A2025-02-2814982Q9UJU5Espacenet
KR 1020250010750 A2025-01-2114982Q9UJU5Espacenet
JP 2024109657 A2024-08-1414821Q9UJU5Espacenet
US 12024722 B22024-07-0232Q9UJU5Espacenet
JP 2023519296 A2023-05-1055Q9UJU5Espacenet
US 11446398 B22022-09-2032534Q9UJU5Espacenet
JP 2022524081 A2022-04-27135505Q9UJU5Espacenet

1 to 10 of 19

See all 19 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants983

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFOXD3 papersNewest fiscal year
P30CA056036Translational Research in Cancer92025
R01DE017914Molecular Interactions during Neural Crest Formation82025
R01DE024157Gene regulatory network controlling neural crest derived formation of facial cartilage72025
P30CA016672Cancer Center Support Grant62025
P01CA163222Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment52025
R01AR043369MITF from control of pigmentation to melanoma risk52025
P30CA008748Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA044579University of Virginia Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025

1 to 10 of 983Source NIH's project files

See all 983 nih grants

Papers1,402

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
GWAS integrating maternal and child genetics reveals novel risk-modifying loci for fetal alcohol spectrum disorders (FASD).Res Sq202642818975PubTator, text miningPubMed
FOXD3 Is Functionally Linked to NF-κB Signaling in KRAS G12C-Mutant NSCLC Cells.Cells202642738858PubTator, text miningPubMed
Partial Replacement of Fish Meal with Fish Scale Meal Enhances Body Color Brightness and Iridophore Development in Koi (Cyprinus carpio var. koi).Animals (Basel)202642511112PubTator, text miningPubMed
SIX1 branchio-oto-renal syndrome variants have different effects on embryonic craniofacial gene expression and cartilage formation.Development202642290293PubTator, text miningPubMed
BRAF inhibitor resistance in melanoma: from resistance mechanisms to therapeutic innovations.Mol Biomed202641807883PubTator, text miningPubMed
A Short Report on Melanocyte/Melanoma Culture, Senescence, and Reproducibility.Pigment Cell Melanoma Res202641807282PubTator, text miningPubMed
Ferroptosis in Parkinson's disease: a review of molecular mechanisms and emerging therapeutic strategies.Front Neurosci202641799880PubTator, text miningPubMed
Genetics of Vitiligo: A Review.Clin Cosmet Investig Dermatol202641789055PubTator, text miningPubMed
FOXC1 Regulates Cytokine Signaling, Inflammatory Pathways, and Retinoid Metabolism to Maintain Limbal Epithelial Cell Homeostasis In Vitro.Int J Mol Sci202641752009PubTator, text miningPubMed
MEP glia share molecular features with oligodendrocytes while maintaining a distinct hybrid signature.MicroPubl Biol202641660199PubTator, text miningPubMed

1 to 10 of 1,402

See all 1,402 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/27022

GET https://conductscience.org/api/genes/v1/27022/patents