Gene · 2705
GJB1: gap junction protein beta 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GJB1: gap junction protein beta 1. Genes, record 2705. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2705
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08034 | Gap junction beta-1 protein | 283 | 15 | Ensembl, GeneID, HGNC |
Source UniProt
Patents66
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47351 | P08034 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 47352 | P08034 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 47353 | P08034 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7963 | P08034 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1718 | P08034 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1718 | P08034 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7963 | P08034 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29007 | P08034 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29008 | P08034 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29010 | P08034 | Espacenet |
1 to 10 of 66
See all 66 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,041
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GJB1 papers | Newest fiscal year |
|---|---|---|---|
| R01GM072631 | Mechanisms of Gap Junction Regulation | 9 | 2025 |
| R01EY012085 | Intercellular Communication in the Eye Lens | 6 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 5 | 2025 |
| P30DK034989 | Yale Liver Center | 5 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 3 | 2025 |
| R01NS072248 | Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome | 3 | 2025 |
| P30AG013319 | San Antonio Nathan Shock Center of Excellence in the Biology of Aging | 2 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 1,041Source NIH's project files
See all 1,041 nih grantsPapers2,865
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Role of liver connexins and pannexins in the development of metabolic dysfunction-associated steatotic liver disease (MASLD) in the context of overnutrition: A narrative review. | Mol Cell Endocrinol | 2027 | 42648696 | PubTator, text mining | PubMed |
| Cardiovascular Autonomic Neuropathy in Charcot-Marie-Tooth Disease: A Genotype-Stratified Study of PMP22 Duplication and GJB1 Mutation Carriers. | J Peripher Nerv Syst | 2026 | 42802036 | PubTator, text mining | PubMed |
| Corneal Confocal Microscopy in Hereditary Demyelinating Neuropathies: Small Fiber Involvement in Charcot-Marie-Tooth Disease. | Muscle Nerve | 2026 | 42736606 | PubTator, text mining | PubMed |
| Two Cases of Multiple Sclerosis in a Family With X-Linked Charcot-Marie-Tooth Disease. | Neurol Genet | 2026 | 42666903 | PubTator, text mining | PubMed |
| [Clinical pattern and evolution of Charcot-Marie-Tooth disease in pediatrics]. | Medicina (B Aires) | 2026 | 42659543 | PubTator, text mining | PubMed |
| [Stroke mimic after wasp sting in a child with Charcot-Marie-Tooth neuropathy X type 1]. | An Sist Sanit Navar | 2026 | 42478917 | PubTator, text mining | PubMed |
| Pediatric stroke-like episodes temporally associated with pollen exposure in GJB1-related CMTX1: an expanded family case report with serial MRI and DTI follow-up. | BMC Pediatr | 2026 | 42477620 | PubTator, text mining | PubMed |
| Spectrum of Hereditary Neuropathies in Adult Patients From Serbia. | J Peripher Nerv Syst | 2026 | 42476530 | PubTator, text mining | PubMed |
| High-Resolution Ultrasound Evaluation of Nerves and Muscles at Multiple Sites in Charcot-Marie-Tooth Disease. | J Ultrasound Med | 2026 | 42435318 | PubTator, text mining | PubMed |
| Functional disease progression in children with inherited peripheral neuropathies: A prospective cohort study. | J Neuromuscul Dis | 2026 | 42396985 | PubTator, text mining | PubMed |
1 to 10 of 2,865
See all 2,865 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2705
GET https://conductscience.org/api/genes/v1/2705/patents?page=2