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BBC3: BCL2 binding component 3

2 proteins, 78 patents, 0 drugs, 0 trials, 4,641 NIH grants and 10,394 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBBC3HGNC
NameBCL2 binding component 3HGNC
NCBI Gene ID27113NCBI Gene
HGNC IDHGNC:17868HGNC
EnsemblENSG00000105327NCBI Gene
AliasesJFY-1, JFY1, PUMANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q96PG8Bcl-2-binding component 3, isoforms 3/42610Ensembl, GeneID, HGNCUniProt
Q9BXH1Bcl-2-binding component 3, isoforms 1/219313Ensembl, GeneID, HGNCUniProt

Patents 78

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026065032 A2026-04-1469Q9BXH1Espacenet
US 12287338 B22025-04-299Q96PG8Espacenet
JP 2025062604 A2025-04-148518Q9BXH1Espacenet
JP 2025062604 A2025-04-148519Q96PG8Espacenet
US 12202866 B22025-01-2143Q9BXH1Espacenet
JP 2024123008 A2024-09-105010Q9BXH1Espacenet
JP 2024123008 A2024-09-105011Q96PG8Espacenet
JP 2023553720 A2023-12-2588Q96PG8Espacenet
JP 2023553720 A2023-12-2591Q9BXH1Espacenet
US 11708396 B22023-07-251937Q9BXH1Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4641

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1142,025NIH's project files
P30CA047904Cancer Center Support Grant422,025NIH's project files
P30CA008748Cancer Center Support Grant392,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)342,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant262,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant222,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant192,025NIH's project files
P30CA016058Cancer Center Support Grant162,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program152,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology152,025NIH's project files

Papers 10394

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818268PubTator, text miningPubMed
42797373PubTator, text miningPubMed
42767173PubTator, text miningPubMed
42693271PubTator, text miningPubMed
42666445PubTator, text miningPubMed
42658927PubTator, text miningPubMed
42650147PubTator, text miningPubMed
42627268PubTator, text miningPubMed
42616599PubTator, text miningPubMed
42599806PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license