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AGO2: argonaute RISC catalytic component 2

1 protein, 33 patents, 0 drugs, 0 trials, 4,703 NIH grants and 13,119 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolAGO2HGNC
Nameargonaute RISC catalytic component 2HGNC
NCBI Gene ID27161NCBI Gene
HGNC IDHGNC:3263HGNC
EnsemblENSG00000123908NCBI Gene
AliasesCASC7, EIF2C2, LESKRES, LINC00980, PPD, Q10, hAGO2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9UKV8Protein argonaute-285967Ensembl, GeneID, HGNCUniProt

Patents 33

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445482Q9UKV8Espacenet
EP 4650780 A22025-11-19476Q9UKV8Espacenet
EP 4641201 A22025-10-29334Q9UKV8Espacenet
JP 2025517969 A2025-06-12334Q9UKV8Espacenet
JP 2025517970 A2025-06-12476Q9UKV8Espacenet
JP 2025062604 A2025-04-146267Q9UKV8Espacenet
EP 4373845 A22024-05-2921Q9UKV8Espacenet
JP 2024515999 A2024-04-1161Q9UKV8Espacenet
JP 2024507735 A2024-02-21140Q9UKV8Espacenet
US 11446398 B22022-09-206267Q9UKV8Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4703

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant362,025NIH's project files
P30CA016672Cancer Center Support Grant272,025NIH's project files
R01GM083300Selective regulatory and biogenesis mechanisms for microRNAs212,025NIH's project files
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis202,025NIH's project files
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging182,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant172,025NIH's project files
R35GM118103Recognition of Cellular Targets by single and double-stranded nucleic acids162,025NIH's project files
R35GM127090Structural and Mechanistic basis for RNA Silencing162,025NIH's project files
R35GM118135Post-transcriptional gene regulation142,025NIH's project files
P30CA045508CSHL Cancer Center Support Grant132,025NIH's project files

Papers 13119

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42815010PubTator, text miningPubMed
42794724PubTator, text miningPubMed
42780509PubTator, text miningPubMed
42778936PubTator, text miningPubMed
42759595PubTator, text miningPubMed
42758358PubTator, text miningPubMed
42749451PubTator, text miningPubMed
42710143PubTator, text miningPubMed
42706794PubTator, text miningPubMed
42699281PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license