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GLA: galactosidase alpha

1 protein, 377 patents, 2 drugs, 20 trials, 1,725 NIH grants and 4,972 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGLAHGNC
Namegalactosidase alphaHGNC
NCBI Gene ID2717NCBI Gene
HGNC IDHGNC:4296HGNC
EnsemblENSG00000102393NCBI Gene
AliasesGALANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06280Alpha-galactosidase A42931Ensembl, GeneID, HGNCUniProt

Patents 377

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026174242 A12026-08-201P06280Espacenet
WO 2026174242 A12026-08-207P06280Espacenet
EP 4777080 A12026-07-221P06280Espacenet
EP 4775262 A22026-07-152P06280Espacenet
JP 2026090534 A2026-06-022P06280Espacenet
JP 2026082813 A2026-05-192P06280Espacenet
JP 2026067851 A2026-04-21271P06280Espacenet
US 12599594 B22026-04-142P06280Espacenet
EP 4704920 A12026-03-1111P06280Espacenet
EP 4704920 A12026-03-11148P06280Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MIGALASTATCHEMBL110458Alpha-galactosidase A stabiliserSTABILISERChEMBL
MIGALASTAT HYDROCHLORIDECHEMBL2107355Alpha-galactosidase A stabiliserSTABILISERChEMBL

Trials 20

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06906367MIGALASTATClinicalTrials.gov
NCT06904261MIGALASTAT HYDROCHLORIDEPHASE3ClinicalTrials.gov
NCT04049760MIGALASTATPHASE32025-06-17ClinicalTrials.gov
NCT04020055MIGALASTATPHASE3ClinicalTrials.gov
NCT03949920MIGALASTATClinicalTrials.gov
NCT03500094MIGALASTATPHASE32021-11-30ClinicalTrials.gov
NCT02194985MIGALASTATPHASE32020-12-21ClinicalTrials.gov
NCT02194985MIGALASTAT HYDROCHLORIDEPHASE32020-12-21ClinicalTrials.gov
NCT01476163MIGALASTAT HYDROCHLORIDEClinicalTrials.gov
NCT01458119MIGALASTAT HYDROCHLORIDEPHASE32018-10-02ClinicalTrials.gov

NIH grants 1725

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
T32GM007546Clinical Pharmacology, Drug Action and Pharmacogenetics162,025NIH's project files
U19AI077439Immune-driven Airway Epithelial Dysfunction in Muco-obstructive Asthma132,025NIH's project files
R01DK067859Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity92,025NIH's project files
R01HL101917Protease Activated Receptor and Thrombomodulin Signaling by coagulation proteases72,025NIH's project files
R01HL049413Structural basis of prothrombin activation62,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award62,025NIH's project files
ZIAES049019Genetic And Environmental Factors In Childhood Respiratory and Allergic Illness52,025NIH's project files
P20GM103429Partnerships for Biomedical Research in Arkansas42,025NIH's project files
R01HL139554Structural enzymology of protein C42,025NIH's project files
R01NS070711Nociceptive Mechanisms Underlying Sickle Cell Pain42,025NIH's project files

Papers 4972

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824750PubTator, text miningPubMed
42824490PubTator, text miningPubMed
42815167PubTator, text miningPubMed
42812888PubTator, text miningPubMed
42810202PubTator, text miningPubMed
42788550PubTator, text miningPubMed
42756359PubTator, text miningPubMed
42748083PubTator, text miningPubMed
42738907PubTator, text miningPubMed
42733264PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license