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SIGLEC8: sialic acid binding Ig like lectin 8
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Gene · 27181

Papers787

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 787

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TitleJournalYearPMIDFound bySource
Eosinophil subtypes in asthmatic patients treated with mepolizumab, omalizumab and dupilumab.ERJ Open Res202642440898PubTator, text miningPubMed
Resident eosinophils in patients with chronic obstructive pulmonary disease: a pilot study.Front Med (Lausanne)202642266944PubTator, text miningPubMed
Targeting immune dysregulation in chronic spontaneous urticaria: beyond antihistamines.Korean J Intern Med202642128382PubTator, text miningPubMed
Treatment of eosinophilic esophagitis with immune modulating agents.Allergy Asthma Proc202642050831PubTator, text miningPubMed
Design, synthesis and biophysical evaluation of sialyl triazoles as glycomimetic ligands for Siglec-8. Sulfonate is a viable replacement for sulfate.Eur J Med Chem202642030707PubTator, text miningPubMed
Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond.Yonsei Med J202641914312PubTator, text miningPubMed
Understanding Eosinophil Heterogeneity: The Known and Unknown.Cells202641892353PubTator, text miningPubMed
Eosinophilia and Risk of Thrombosis and Mortality in Hospitalized Patients: A Retrospective Cohort Study.Life (Basel)202641752879PubTator, text miningPubMed
The Role of Mucins in Esophageal Inflammatory Diseases.J Pers Med202641745385PubTator, text miningPubMed
An Assessment of Melatonin Levels in the Saliva of Patients with Chronic Urticaria in Comparison with Their Sleep Quality and Dermatologic Quality of Life.Clin Pract202641744519PubTator, text miningPubMed
Solitary chemosensory cells amplify eosinophilic inflammation via PAR-2 activation in house dust mite-sensitized allergic rhinitis.World Allergy Organ J202641717077PubTator, text miningPubMed
Natural Killer Cell Dysfunction Causes Eosinophil Accumulation in Chronic Rhinosinusitis With Nasal Polyps.Clin Transl Allergy202641702868PubTator, text miningPubMed
Systemic Mastocytosis, KIT and the Effects of KIT Tyrosine Kinase Inhibitors on Mast Cell and Basophil Activation.Curr Allergy Asthma Rep202641701410PubTator, text miningPubMed
Systemic Treatments for Chronic Spontaneous Urticaria: Anti-IgE and Beyond.J Allergy Clin Immunol Pract202641654334PubTator, text miningPubMed
Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis.Cell Death Dis202641526335PubTator, text miningPubMed
Eosinophils (EOS): the Greek dawn goddess of the same name.J Leukoc Biol202641347958PubTator, text miningPubMed
MRGPRX2-expressing mast cells are increased in the GI tract of individuals with active inflammatory bowel disease and hereditary α-tryptasemia.Front Allergy202541647192PubTator, text miningPubMed
Low IgE and absence of sensitization in non-T2 asthma: a transcriptomic and cytokine study.Front Immunol202541601686PubTator, text miningPubMed
MRGPRX2-expressing mast cells are increased in the GI tract of individuals with active inflammatory bowel disease and hereditary α-tryptasemia.medRxiv202541503473PubTator, text miningPubMed
Identification and Validation of Differentially Expressed mRNAs From Peripheral Leukocytes for Acute Stanford Type A Aortic Dissection.J Am Heart Assoc202541378480PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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