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Gene · 27189

IL17C: interleukin 17C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IL17C: interleukin 17C. Genes, record 27189. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27189

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Gene

Symbol
IL17C
HGNC
Name
interleukin 17C
HGNC
NCBI Gene ID
27189
NCBI Gene
HGNC ID
HGNC:5983
HGNC
Ensembl
ENSG00000124391
NCBI Gene
Aliases
CX2, IL-17C, IL-21, MGC126884, MGC138401
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9P0M4Interleukin-17C1970Ensembl, GeneID, HGNC

Source UniProt

Patents283

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4731677 A22026-04-2985Q9P0M4Espacenet
EP 4650780 A22025-11-191121Q9P0M4Espacenet
US 12473363 B22025-11-18910Q9P0M4Espacenet
JP 2025147176 A2025-10-066901Q9P0M4Espacenet
JP 2025529142 A2025-09-046703Q9P0M4Espacenet
EP 4591879 A22025-07-3035Q9P0M4Espacenet
US 12371689 B22025-07-296703Q9P0M4Espacenet
JP 2025517970 A2025-06-121121Q9P0M4Espacenet
WO 2025081160 A12025-04-1756Q9P0M4Espacenet
JP 2025028160 A2025-02-286901Q9P0M4Espacenet

1 to 10 of 283

See all 283 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants723

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL17C papersNewest fiscal year
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success102025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center82025
R37DE022550Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis72025
T32AR007197Training Grant in Cell and Molecular Dermatology62025
P01AI108545Synergies among inhibitory receptors in tolerance and disease32025
P30AG028716Duke Claude D. Pepper Older Americans Independence Center32025
P30AR075049Northwestern University Skin Biology and Diseases Resource-based Center32025
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy32025
U24CA224319High-Dimensional Immune Monitoring of NCI-Supported Immunotherapy Trials32025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 723Source NIH's project files

See all 723 nih grants

Papers1,552

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploration of cytokines relating to masked obesity in Japanese women.Endocrine202642803886PubTator, text miningPubMed
Association of Vitamin D Levels and Systemic Inflammation in Patients with Hashimoto's Thyroiditis.Diseases202642783242PubTator, text miningPubMed
Sensor-Detected Hypoglycaemia Is Associated With Inflammatory Protein and Immune Cell Alterations in People With Diabetes: Findings From the Hypo-METRICS Study.Diabetes Obes Metab202642755124PubTator, text miningPubMed
Flagellar regulation in enterotoxigenic E. coli modulates innate immune activation.Infect Immun202642752214PubTator, text miningPubMed
Ex vivo Evaluation of Live-MB2 and CX-2 Biotic Strains on Inflammatory and Barrier-Related Biomarkers in a Human Skin Atopic Dermatitis-Like Model.Clin Cosmet Investig Dermatol202642732409PubTator, text miningPubMed
Single-Nucleus and Multiomics Profiling of Epicardial Adipose Tissue in Atrial Fibrillation Reveals Novel Mechanisms and Translational Biomarkers.J Am Heart Assoc202642657754PubTator, text miningPubMed
Targeting the IL-17C-M2 macrophage axis ameliorates fibrosis in endometriosis through MAPK/ERK signaling.J Transl Med202642568086PubTator, text miningPubMed
[Bidirectional two-sample MR analysis of causal relationships between human inflammatory proteins and HS and keloids].Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi202642547441PubTator, text miningPubMed
Increased Interleukin-17C Production by the Toll-Like Receptor 3 Ligand Poly(I:C) in Primary Cystic Fibrosis Airway Epithelial Cells.Biol Pharm Bull202642528204PubTator, text miningPubMed
Identification of a robust multitarget protein panel for Parkinson's disease via absolute quantification and large-scale external replication.Brain Commun202642516760PubTator, text miningPubMed

1 to 10 of 1,552

See all 1,552 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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