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PDCD4: programmed cell death 4

1 protein, 49 patents, 0 drugs, 0 trials, 1,992 NIH grants and 5,106 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDCD4HGNC
Nameprogrammed cell death 4HGNC
NCBI Gene ID27250NCBI Gene
HGNC IDHGNC:8763HGNC
EnsemblENSG00000150593NCBI Gene
AliasesH731NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q53EL6Programmed cell death protein 446911Ensembl, GeneID, HGNCUniProt

Patents 49

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193075Q53EL6Espacenet
EP 4641201 A22025-10-292630Q53EL6Espacenet
JP 2025517969 A2025-06-122630Q53EL6Espacenet
JP 2025517970 A2025-06-123075Q53EL6Espacenet
JP 2024178415 A2024-12-248233Q53EL6Espacenet
JP 2024123008 A2024-09-107813Q53EL6Espacenet
US 11446398 B22022-09-2066801Q53EL6Espacenet
JP 2022529532 A2022-06-228233Q53EL6Espacenet
JP 2022524081 A2022-04-27169772Q53EL6Espacenet
US 11015221 B22021-05-2549Q53EL6Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1992

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant312,025NIH's project files
P30CA016058Cancer Center Support Grant172,025NIH's project files
P30CA056036Translational Research in Cancer82,025NIH's project files
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant82,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
R01CA249180Targeted degradation of RNAs by using small molecules62,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202852,025NIH's project files
P30CA042014Cancer Center Support Grant42,025NIH's project files
P30CA068485Cancer Center Support Grant42,025NIH's project files
P30CA124435Stanford Cancer Institute42,025NIH's project files

Papers 5106

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42802951PubTator, text miningPubMed
42648032PubTator, text miningPubMed
42640698PubTator, text miningPubMed
42548314PubTator, text miningPubMed
42373273PubTator, text miningPubMed
42350583PubTator, text miningPubMed
42319574PubTator, text miningPubMed
42293239PubTator, text miningPubMed
42287537PubTator, text miningPubMed
42216960PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license