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Gene · 27306

HPGDS: hematopoietic prostaglandin D synthase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HPGDS: hematopoietic prostaglandin D synthase. Genes, record 27306. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27306

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Gene

Symbol
HPGDS
HGNC
Name
hematopoietic prostaglandin D synthase
HGNC
NCBI Gene ID
27306
NCBI Gene
HGNC ID
HGNC:17890
HGNC
Ensembl
ENSG00000163106
NCBI Gene
Aliases
GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60760Hematopoietic prostaglandin D synthase19930Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448869O60760Espacenet
US 12023385 B22024-07-0220O60760Espacenet
EP 4119552 A12023-01-1834O60760Espacenet
US 11446398 B22022-09-2037625O60760Espacenet
JP 2022524081 A2022-04-27140596O60760Espacenet
US 11311609 B22022-04-2634O60760Espacenet
US 11293023 B22022-04-0520O60760Espacenet
US 11078247 B22021-08-035142O60760Espacenet
US 11046954 B22021-06-2934O60760Espacenet
JP 2020513789 A2020-05-2126O60760Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants960

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHPGDS papersNewest fiscal year
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease92025
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis62025
T32AI007306Immunologic Basis of Resistance and Hypersensitivity62025
U19AI070235Epithelial Genes in Allergic Inflammation62025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)52025
P30ES010126UNC Center for Environmental Health and Susceptibility52025
U19AI095219Pathophysiologic and Therapeutic Mechanisms of Aspirin Exacerbated Respiratory Disease52025
P30CA068485Cancer Center Support Grant42025
P30ES009089Center for Environmental Health in Northern Manhattan42025
R01AI078908Control of Pulmonary Inflammation by Leukotriene E442025

1 to 10 of 960Source NIH's project files

See all 960 nih grants

Papers1,644

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Matrine-Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle.Integr Zool202642713821PubTator, text miningPubMed
Single-cell RNA sequencing uncovers an immunosuppressive program in PDAC mast cells: tumour-driven activation, proliferation, and association with Treg recruitment.Ann Med202642675914PubTator, text miningPubMed
Transcriptome-Based Six-Gene Fatty Acid Metabolism Signature for Prognosis and Predicted Immunotherapy Response in Lung Adenocarcinoma: Cross-Population Validation.Genes (Basel)202642650107PubTator, text miningPubMed
Association of HPGDS Expression with Prognosis and Immune Microenvironment Remodeling in Pancreatic Cancer.Cancer Manag Res202642610087PubTator, text miningPubMed
Functional Characterization and Inhibition Analysis of a Glutathione Transferase from Cryptosporidium parvum: A Potential Target for Antiparasitic Drug Development.Pharmaceuticals (Basel)202642515788PubTator, text miningPubMed
Significance of Tuft Cells Expressing Hematopoietic Prostaglandin D Synthase During the Pathogenesis of Eosinophilic Chronic Rhinosinusitis.Biomedicines202642512007PubTator, text miningPubMed
Frailty-related plasma proteomic signatures and key biomarkers for new-onset dementia and its subtypes: A prospective cohort study.J Adv Res202642468803PubTator, text miningPubMed
Longitudinal plasma proteomics separates diagnostic differences from progression-linked changes in Alzheimer's disease.medRxiv202642465883PubTator, text miningPubMed
CYP4B1 Expression in Breast Cancer: An Immunohistochemical Study with Complementary in silico Analyses.Breast Cancer (Dove Med Press)202642436652PubTator, text miningPubMed
Presence of Tuft Cells Expressing Hematopoietic Prostaglandin D Synthase in Acinar-to-Ductal Metaplasia in Human Obstructive Pancreatitis.Curr Issues Mol Biol202642353590PubTator, text miningPubMed

1 to 10 of 1,644

See all 1,644 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/27306

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