Gene · 27338
UBE2S: ubiquitin conjugating enzyme E2 S
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. UBE2S: ubiquitin conjugating enzyme E2 S. Genes, record 27338. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27338
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16763 | Ubiquitin-conjugating enzyme E2 S | 222 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69088 | Q16763 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4584 | Q16763 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4584 | Q16763 | Espacenet |
| JP 2023550743 A | 2023-12-05 | 96 | Q16763 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 95272 | Q16763 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 198243 | Q16763 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12243 | Q16763 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 249523 | Q16763 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 249523 | Q16763 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 249523 | Q16763 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,055
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | UBE2S papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 19 | 2025 |
| R35GM128855 | Spindle Assembly Checkpoint Silencing | 12 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 8 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| R01GM065334 | Solution structure and dynamics of polyubiquitin chains | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| T32GM135095 | Pharmacological Sciences Training Program | 4 | 2025 |
| P20GM103440 | Nevada IDeA Networks of Biomedical Research Excellence (INBRE) | 3 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 3 | 2025 |
1 to 10 of 1,055Source NIH's project files
See all 1,055 nih grantsPapers1,523
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Structural determinants for FAT10 activation and transfer from UBA6 to E2 enzymes. | Nat Commun | 2026 | 42733088 | PubTator, text mining | PubMed |
| UBE2S Promotes KIRC Progression by Regulating CDC20 Expression and Suppressing FDX1-Mediated Cuproptosis, While Promoting M2 Macrophage Polarization. | Mol Carcinog | 2026 | 42669192 | PubTator, text mining | PubMed |
| Identification and Validation of an E2F Targets-Related Gene Signature Risk Score Predicting the Prognosis of Patients with Uveal Melanoma. | Ocul Oncol Pathol | 2026 | 42553888 | PubTator, text mining | PubMed |
| UBE2S emerges as a key driver in an NK cell-based prognostic model for clear cell renal cell carcinoma. | PLoS One | 2026 | 42133651 | PubTator, text mining | PubMed |
| The backside β-turn is a key structural element of Rad6-family E2 ubiquitin-conjugating enzymes. | Biochem J | 2026 | 42095445 | PubTator, text mining | PubMed |
| UBE2S promotes small cell lung cancer transformation and progression via monitoring metabolic remodeling and cell cycle. | J Transl Med | 2026 | 42032653 | PubTator, text mining | PubMed |
| A palmitoylation-related prognostic risk scoring model and tumor microenvironment characterization in lung adenocarcinoma, using single-cell RNA sequencing data. | Comput Biol Chem | 2026 | 41985273 | PubTator, text mining | PubMed |
| OTUB1 stabilizes PRRSV matrix protein through a non-canonical deubiquitination mechanism to promote viral replication. | J Virol | 2026 | 41914757 | PubTator, text mining | PubMed |
| The Regulation of p53 by Ubiquitination and Implications for Therapeutic Targeting in Colorectal Cancer. | Genes (Basel) | 2026 | 41898804 | PubTator, text mining | PubMed |
| HNRNPH1 drives glioblastoma progression by regulating the splicing of cell cycle genes. | Cell Death Dis | 2026 | 41872153 | PubTator, text mining | PubMed |
1 to 10 of 1,523
See all 1,523 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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