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Gene · 27343

POLL: DNA polymerase lambda

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. POLL: DNA polymerase lambda. Genes, record 27343. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27343

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Gene

Symbol
POLL
HGNC
Name
DNA polymerase lambda
HGNC
NCBI Gene ID
27343
NCBI Gene
HGNC ID
HGNC:9184
HGNC
Ensembl
ENSG00000166169
NCBI Gene
Aliases
BETAN, POLKAPPA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UGP5DNA polymerase lambda57597Ensembl, GeneID, HGNC

Source UniProt

Patents114

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4780952 A12026-07-2965Q9UGP5Espacenet
US 12435331 B22025-10-0755Q9UGP5Espacenet
JP 2025147176 A2025-10-0610626Q9UGP5Espacenet
JP 2025147176 A2025-10-0610627Q9UGP5Espacenet
JP 2025147176 A2025-10-0610628Q9UGP5Espacenet
JP 2025529142 A2025-09-047400Q9UGP5Espacenet
US 12371689 B22025-07-297400Q9UGP5Espacenet
JP 2025028160 A2025-02-2810626Q9UGP5Espacenet
JP 2025028160 A2025-02-2810627Q9UGP5Espacenet
JP 2025028160 A2025-02-2810628Q9UGP5Espacenet

1 to 10 of 114

See all 114 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,104

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePOLL papersNewest fiscal year
ZIAES065070Structure-Function Studies Of DNA Replication Fidelity232025
ZIAHD001500DNA Replication, Repair, and Mutagenesis In Eukaryotic And Prokaryotic Cells122025
P30CA068485Cancer Center Support Grant102025
P01CA092584Structural Cell Biology of DNA Repair Machines82025
P30ES010126UNC Center for Environmental Health and Susceptibility82025
R01CA097096DNA Polymerases in Nonhomologous End Joining82025
T32ES018827Research Training in Environmental Toxicology82025
P30CA016086Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
R01CA080024Intra and Extra-Chromosomal Probes for Mutagenesis by Carcinogens62025

1 to 10 of 1,104Source NIH's project files

See all 1,104 nih grants

Papers1,899

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Structural insight into human Y-family polymerases and mechanistic basis of translesion synthesis of key DNA damages.Mutat Res Rev Mutat Res202642767445PubTator, text miningPubMed
DNA-Peptide Crosslinks Placed at Codon 249 of the p53 Tumor Suppressor Gene Induce G to A Transitions in Human Cells.Chembiochem202642627024PubTator, text miningPubMed
Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance.Proc Natl Acad Sci U S A202642607204PubTator, text miningPubMed
[Analysis of Thalassemia Genotypes and Clinical Phenotypes in Liuzhou, Guangxi].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642227447PubTator, text miningPubMed
Polymerase κ Recruits DDX23 To Promote R-Loop Resolution.Anal Chem202641949541PubTator, text miningPubMed
A Comparative Study for the Incorporation of 8-oxo-dATP in DNA by Human DNA Polymerases.Int J Mol Sci202641898401PubTator, text miningPubMed
Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing.Nucleic Acids Res202641891877PubTator, text miningPubMed
Establishment of a novel gene panel for prognosis assessment in patients with lower grade glioma.Medicine (Baltimore)202641760070PubTator, text miningPubMed
An Integrated Genotyping Strategy for α/β-Thalassemia: Based on the Analysis of the Coding Sequences and Expression Levels of HBA2, HBA1, and HBB in Peripheral Blood mRNA.J Clin Lab Anal202641735777PubTator, text miningPubMed
DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining.Nucleic Acids Res202641700088PubTator, text miningPubMed

1 to 10 of 1,899

See all 1,899 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/27343

GET https://conductscience.org/api/genes/v1/27343/patents?page=2