Gene · 27343
POLL: DNA polymerase lambda
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. POLL: DNA polymerase lambda. Genes, record 27343. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/27343
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UGP5 | DNA polymerase lambda | 575 | 97 | Ensembl, GeneID, HGNC |
Source UniProt
Patents114
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4780952 A1 | 2026-07-29 | 65 | Q9UGP5 | Espacenet |
| US 12435331 B2 | 2025-10-07 | 55 | Q9UGP5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10626 | Q9UGP5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10627 | Q9UGP5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10628 | Q9UGP5 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7400 | Q9UGP5 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7400 | Q9UGP5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10626 | Q9UGP5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10627 | Q9UGP5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10628 | Q9UGP5 | Espacenet |
1 to 10 of 114
See all 114 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,104
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | POLL papers | Newest fiscal year |
|---|---|---|---|
| ZIAES065070 | Structure-Function Studies Of DNA Replication Fidelity | 23 | 2025 |
| ZIAHD001500 | DNA Replication, Repair, and Mutagenesis In Eukaryotic And Prokaryotic Cells | 12 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 10 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 8 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 8 | 2025 |
| R01CA097096 | DNA Polymerases in Nonhomologous End Joining | 8 | 2025 |
| T32ES018827 | Research Training in Environmental Toxicology | 8 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01CA080024 | Intra and Extra-Chromosomal Probes for Mutagenesis by Carcinogens | 6 | 2025 |
1 to 10 of 1,104Source NIH's project files
See all 1,104 nih grantsPapers1,899
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Structural insight into human Y-family polymerases and mechanistic basis of translesion synthesis of key DNA damages. | Mutat Res Rev Mutat Res | 2026 | 42767445 | PubTator, text mining | PubMed |
| DNA-Peptide Crosslinks Placed at Codon 249 of the p53 Tumor Suppressor Gene Induce G to A Transitions in Human Cells. | Chembiochem | 2026 | 42627024 | PubTator, text mining | PubMed |
| Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance. | Proc Natl Acad Sci U S A | 2026 | 42607204 | PubTator, text mining | PubMed |
| [Analysis of Thalassemia Genotypes and Clinical Phenotypes in Liuzhou, Guangxi]. | Zhongguo Shi Yan Xue Ye Xue Za Zhi | 2026 | 42227447 | PubTator, text mining | PubMed |
| Polymerase κ Recruits DDX23 To Promote R-Loop Resolution. | Anal Chem | 2026 | 41949541 | PubTator, text mining | PubMed |
| A Comparative Study for the Incorporation of 8-oxo-dATP in DNA by Human DNA Polymerases. | Int J Mol Sci | 2026 | 41898401 | PubTator, text mining | PubMed |
| Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing. | Nucleic Acids Res | 2026 | 41891877 | PubTator, text mining | PubMed |
| Establishment of a novel gene panel for prognosis assessment in patients with lower grade glioma. | Medicine (Baltimore) | 2026 | 41760070 | PubTator, text mining | PubMed |
| An Integrated Genotyping Strategy for α/β-Thalassemia: Based on the Analysis of the Coding Sequences and Expression Levels of HBA2, HBA1, and HBB in Peripheral Blood mRNA. | J Clin Lab Anal | 2026 | 41735777 | PubTator, text mining | PubMed |
| DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining. | Nucleic Acids Res | 2026 | 41700088 | PubTator, text mining | PubMed |
1 to 10 of 1,899
See all 1,899 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/27343
GET https://conductscience.org/api/genes/v1/27343/patents?page=2