Gene · 2737
GLI3: GLI family zinc finger 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GLI3: GLI family zinc finger 3. Genes, record 2737. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2737
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P10071 | Transcription activator GLI3 | 1,580 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents35
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47570 | P10071 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11337 | P10071 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11816 | P10071 | Espacenet |
| JP 2025155288 A | 2025-10-14 | 2 | P10071 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15045 | P10071 | Espacenet |
| JP 2025521922 A | 2025-07-10 | 61 | P10071 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11816 | P10071 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11337 | P10071 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29068 | P10071 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15045 | P10071 | Espacenet |
1 to 10 of 35
See all 35 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,274
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GLI3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 17 | 2025 |
| ZIAHG200328 | Rare & Mosaic Disorders Molecular Research | 16 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 13 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 10 | 2025 |
| R01HD073151 | Cis-regulatory circuitry underlying Hedgehog mediated limb development | 9 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 6 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 6 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 6 | 2025 |
| R01GM060992 | Intraflagellar Transport Proteins in Mice | 6 | 2025 |
| R35GM118063 | Cell signaling in development and regeneration | 6 | 2025 |
1 to 10 of 2,274Source NIH's project files
See all 2,274 nih grantsPapers3,698
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genetic landscape of pediatric seizures in Southeast China: identification of a novel GLI3 frameshift variant through whole-exome sequencing. | Ann Med Surg (Lond) | 2026 | 42724907 | PubTator, text mining | PubMed |
| Sharp cell type boundaries emerge from coordinated morphogen signaling. | Genes Dev | 2026 | 42722434 | PubTator, text mining | PubMed |
| Molecular insights into uterine fibroids: crosstalk between SHH and Wnt pathways, DNA methylation, and miRNAs regulation. | Mol Genet Genomics | 2026 | 42667406 | PubTator, text mining | PubMed |
| Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn's disease. | Nat Immunol | 2026 | 42587037 | PubTator, text mining | PubMed |
| Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1. | Oncol Rep | 2026 | 42495774 | PubTator, text mining | PubMed |
| GLI3 in cancer: a context-dependent regulator with diagnostic, prognostic, and therapeutic potential. | Front Immunol | 2026 | 42488637 | PubTator, text mining | PubMed |
| Genomic Landscape and Perinatal Outcomes of Fetal Polydactyly: A Retrospective Cohort Study Integrating CNV-seq and Trio-ES. | Prenat Diagn | 2026 | 42390887 | PubTator, text mining | PubMed |
| MIRAGE: a multimodal deep learning framework for interpretable risk assessment of high myopia from genetic and retinal imaging data. | Hum Mol Genet | 2026 | 42262223 | PubTator, text mining | PubMed |
| Reciprocal Regulation of GLI1 and GLI3 Fine Tunes the Pathogenic Behavior of Synovial Fibroblasts in Rheumatoid Arthritis. | Int J Rheum Dis | 2026 | 42246142 | PubTator, text mining | PubMed |
| Novel MYH11::GLI3 fusion in ileal leiomyoma. | Pathol Oncol Res | 2026 | 42051689 | PubTator, text mining | PubMed |
1 to 10 of 3,698
See all 3,698 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2737
GET https://conductscience.org/api/genes/v1/2737/patents?page=2