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Gene · 2746

GLUD1: glutamate dehydrogenase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GLUD1: glutamate dehydrogenase 1. Genes, record 2746. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2746

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Gene

Symbol
GLUD1
HGNC
Name
glutamate dehydrogenase 1
HGNC
NCBI Gene ID
2746
NCBI Gene
HGNC ID
HGNC:4335
HGNC
Ensembl
ENSG00000148672
NCBI Gene
Aliases
GDH, GDH1, GLUD, hGDH1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P00367Glutamate dehydrogenase 1, mitochondrial5587Ensembl, GeneID, HGNC

Source UniProt

Patents64

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21180P00367Espacenet
JP 2026004568 A2026-01-1447688P00367Espacenet
EP 4650780 A22025-11-193001P00367Espacenet
WO 2025229128 A12025-11-0629P00367Espacenet
EP 4641201 A22025-10-292574P00367Espacenet
JP 2025147176 A2025-10-066048P00367Espacenet
JP 2025529142 A2025-09-046512P00367Espacenet
US 12371689 B22025-07-296512P00367Espacenet
JP 2025517969 A2025-06-122574P00367Espacenet
JP 2025517970 A2025-06-123001P00367Espacenet

1 to 10 of 64

See all 64 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,901

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGLUD1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant142025
P30CA016672Cancer Center Support Grant122025
P30DK019525University of Pennsylvania Diabetes Research Center122025
P01CA117969Genetics and Biology of Pancreatic Ductal Adenocarcinoma102025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes62025
P30CA030199Cancer Center Support Grant (CCSG)52025
P30CA138292Winship Cancer Institute Cancer Center Support Grant52025
T32DK007314Diabetes, Endocrine, and Metabolism52025
P30CA006516Dana-Farber/Harvard Cancer Center42025
P30CA016086Cancer Center Support Grant42025

1 to 10 of 1,901Source NIH's project files

See all 1,901 nih grants

Papers4,000

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Investigation of geographical differences among Giardia duodenalis assemblage B populations using diverse haplotypes identified by cloning of PCR amplicons.Parasitol Int202742632615PubTator, text miningPubMed
Comparative genomics of nitrogen acquisition and assimilation gene-family copy-number architecture across chlorophytes.World J Microbiol Biotechnol202642821022PubTator, text miningPubMed
α-KG conformationally stabilizes nuclear GLUD1-SNAIL complex to fuel trans-endothelial migration in metastasis.Nat Commun202642816486PubTator, text miningPubMed
Moderately elevated salinity rapidly promotes oyster meat yield by rewiring ammonia transport and metabolic networks.Comp Biochem Physiol Part D Genomics Proteomics202642815400PubTator, text miningPubMed
A Thieno[3,2-D] pyrimidine class of p110α/GDH1 dual inhibitor SBS-873 suppresses TNBC growth by inhibiting PI3K/mTOR signaling and inducing ferroptosis through glutathione depletion.Cell Signal202642800624PubTator, text miningPubMed
Current practices and unmet needs in the management of Clostridioides difficile infection in pediatric inflammatory bowel disease: A national survey.J Pediatr Gastroenterol Nutr202642755036PubTator, text miningPubMed
Clostridioides (Clostridium) Difficile Infection in the First Year after Hematopoietic Stem Cell Transplantation: A Single Center Experience from a Tertiary Care Center in India.Indian J Hematol Blood Transfus202642712690PubTator, text miningPubMed
Clostridioides difficile in Paediatric Inflammatory Bowel Disease: A Retrospective Cross-Sectional Analysis of the East London Region.J Paediatr Child Health202642706877PubTator, text miningPubMed
High-molecular-weight glutenin subunit alleles and compositions modulate gluten quality and dough rheology in 20 wheat near-isogenic lines.J Sci Food Agric202642706681PubTator, text miningPubMed
Integrated multi-omics analysis of metabolomics and proteomics uncovers dysregulated amino acid metabolism in HCC metastasis.Front Immunol202642688489PubTator, text miningPubMed

1 to 10 of 4,000

See all 4,000 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2746

GET https://conductscience.org/api/genes/v1/2746/patents?page=2