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Gene · 2767

GNA11: G protein subunit alpha 11

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GNA11: G protein subunit alpha 11. Genes, record 2767. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2767

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Gene

Symbol
GNA11
HGNC
Name
G protein subunit alpha 11
HGNC
NCBI Gene ID
2767
NCBI Gene
HGNC ID
HGNC:4379
HGNC
Ensembl
ENSG00000088256
NCBI Gene
Aliases
FBH, FBH2, FHH2, GNA-11, HG1K, HHC2, HYPOC2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P29992Guanine nucleotide-binding protein subunit alpha-1135913Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026053553 A2026-03-25152P29992Espacenet
JP 2026004568 A2026-01-1448437P29992Espacenet
EP 4650780 A22025-11-19101P29992Espacenet
WO 2025224050 A12025-10-304P29992Espacenet
JP 2025517970 A2025-06-12101P29992Espacenet
JP 2025063038 A2025-04-15270P29992Espacenet
EP 4516806 A22025-03-05152P29992Espacenet
EP 4406555 A22024-07-31270P29992Espacenet
JP 2024088757 A2024-07-02270P29992Espacenet
JP 2024069247 A2024-05-21152P29992Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,500

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGNA11 papersNewest fiscal year
P30CA008748Cancer Center Support Grant582025
P30CA016672Cancer Center Support Grant452025
P30EY014801Miami Center for Vision Research112025
K12CA090625Vanderbilt Clinical Oncology Research Career Development Award102025
P30CA016058Cancer Center Support Grant102025
P30CA056036Translational Research in Cancer102025
P30CA010815Consolidated Basic Cancer Research Program92025
P30CA068485Cancer Center Support Grant92025
P30CA016086Cancer Center Support Grant82025
R01CA257505Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma82025

1 to 10 of 1,500Source NIH's project files

See all 1,500 nih grants

Papers2,923

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical and molecular characterization of non-PIK3CA-related vascular malformations with overgrowth in a pediatric cohort.World J Pediatr202642814223PubTator, text miningPubMed
Case report: A Newly Identified G-protein Subunit α-11 Loss-of-Function Variant Causing Familial Hypocalciuric Hypercalcemia Type 2 in an Italian Kindred.Front Endocrinol (Lausanne)202642787214PubTator, text miningPubMed
Peripheral vasomotor symptoms: Expanding the phenotype of GNA11-related capillary malformations.J Eur Acad Dermatol Venereol202642755085PubTator, text miningPubMed
Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes.Brain Pathol202642740583PubTator, text miningPubMed
Significantly elevated calcium levels and gallstone disease in a patient with familial hypocalciuric hypercalcaemia.Endocrinol Diabetes Metab Case Rep202642709961PubTator, text miningPubMed
Abnormal Enamel Mineralization and Hypercalcemia due to GNA11 Variants.J Dent Res202642670332PubTator, text miningPubMed
SUMOylation-Driven Subtype Heterogeneity and Prognostic Biomarkers in Renal Cell Carcinoma.Curr Issues Mol Biol202642651750PubTator, text miningPubMed
Does the ERBB/EGF Signaling Network Serve as a Nexus for Oncogenic Signals in Uveal Melanoma?Biomolecules202642650747PubTator, text miningPubMed
Primary diffuse leptomeningeal melanomatosis presenting as chronic meningitis and dense spinal plaques.Pract Neurol202642613178PubTator, text miningPubMed
SMARCB1 (INI1)-deficient malignant melanocytic neoplasm with histologically confirmed vertebral metastases in a young adult: a case report.Front Oncol202642528567PubTator, text miningPubMed

1 to 10 of 2,923

See all 2,923 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2767

GET https://conductscience.org/api/genes/v1/2767/patents?page=2