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Gene · 2768

GNA12: G protein subunit alpha 12

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GNA12: G protein subunit alpha 12. Genes, record 2768. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2768

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Gene

Symbol
GNA12
HGNC
Name
G protein subunit alpha 12
HGNC
NCBI Gene ID
2768
NCBI Gene
HGNC ID
HGNC:4380
HGNC
Ensembl
ENSG00000146535
NCBI Gene
Aliases
HG1M1, NNX3, RMP, gep
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03113Guanine nucleotide-binding protein subunit alpha-123811Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026053553 A2026-03-25155Q03113Espacenet
JP 2026004568 A2026-01-1448434Q03113Espacenet
EP 4650780 A22025-11-192943Q03113Espacenet
JP 2025517970 A2025-06-122943Q03113Espacenet
US 12269900 B22025-04-0811Q03113Espacenet
JP 2025032204 A2025-03-1129117Q03113Espacenet
US 12247244 B22025-03-114Q03113Espacenet
EP 4516806 A22025-03-05155Q03113Espacenet
EP 4461818 A22024-11-1329117Q03113Espacenet
JP 2024069247 A2024-05-21155Q03113Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,203

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGNA12 papersNewest fiscal year
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital52025
P30CA016086Cancer Center Support Grant42025
R01MH054137Structure and Function of Dopamine Receptors42025
U01DK062413Determining genomic and host-environment contributions to IBD phenotypes42025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025
R01DA036596Regulation of Neuronal GPCR Signaling32025
R35GM136397GPCR anterograde trafficking32025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations32025

1 to 10 of 1,203Source NIH's project files

See all 1,203 nih grants

Papers1,325

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Heterotrimeric G proteins containing Gβ1γ2 subunits exhibit subtype-specific mobility differences in live cells.PLoS One202642809568PubTator, text miningPubMed
Potential role of 5-HT7 receptor antagonists in the treatment of depression: Pharmacological and bioengineering perspectives.Prog Neuropsychopharmacol Biol Psychiatry202642700946PubTator, text miningPubMed
DNAm landscape up to 4 months post SARS-CoV-2 infection: insights from four population-based cohorts.Clin Epigenetics202642288901PubTator, text miningPubMed
Protease-activated receptor 1 as an endogenous model of peptidergic Gαq-Gα12-biased G protein signaling.Front Mol Biosci202642267118PubTator, text miningPubMed
Conserved residues in the Gα interface show subtype specificity in Gβγ coupling.J Biol Chem202642248450PubTator, text miningPubMed
In vitro pharmacological profile of the TSH receptor-stimulating autoantibodies, M22 and K1-18.Biochem Pharmacol202642218985PubTator, text miningPubMed
The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho-Associated Protein Kinase-Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis.
Arthritis Rheumatol202642206826PubTator, text miningPubMed
GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy.Nat Commun202642014397PubTator, text miningPubMed
Machine learning-predicted chromatin organization landscape across pediatric tumors.Sci Rep202641904260PubTator, text miningPubMed
The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets.Cells202641892342PubTator, text miningPubMed

1 to 10 of 1,325

See all 1,325 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2768

GET https://conductscience.org/api/genes/v1/2768/patents?page=2