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GNAI1: G protein subunit alpha i1

1 protein, 43 patents, 0 drugs, 0 trials, 5,645 NIH grants and 8,816 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGNAI1HGNC
NameG protein subunit alpha i1HGNC
NCBI Gene ID2770NCBI Gene
HGNC IDHGNC:4384HGNC
EnsemblENSG00000127955NCBI Gene
AliasesGi, HG1B, NEDHISBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P63096Guanine nucleotide-binding protein G(i) subunit alpha-1354651Ensembl, GeneID, HGNCUniProt

Patents 43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12618828 B22026-05-0557P63096Espacenet
JP 2026053553 A2026-03-25143P63096Espacenet
JP 2026004568 A2026-01-1448451P63096Espacenet
EP 4650780 A22025-11-196780P63096Espacenet
JP 2025517970 A2025-06-126780P63096Espacenet
US 12252521 B22025-03-1857P63096Espacenet
US 12247244 B22025-03-117P63096Espacenet
EP 4516806 A22025-03-05143P63096Espacenet
US 12084418 B22024-09-101P63096Espacenet
JP 2024069247 A2024-05-21143P63096Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5645

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIADK031117Development of Drugs Acting at Adenosine Receptors342,025NIH's project files
ZIADA000493Functional and Pharmacological Significance of Receptor Heteromers in the CNS242,025NIH's project files
ZIADK031116Development of P2Y Receptor Ligands242,025NIH's project files
R01HL016037Molecular Regulation of Cardiovascular 7 TM Receptors162,025NIH's project files
R35GM128641Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation162,025NIH's project files
ZIADK031126Computer Modeling of G Protein-Coupled Receptors142,025NIH's project files
P01CA049605Bone Marrow Grafting and Cellular Therapy for Leukemia and Lymphoma112,025NIH's project files
P30CA016672Cancer Center Support Grant102,025NIH's project files
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis102,025NIH's project files
R01MH112205Molecular Details of Psychoactive Drug Actions102,025NIH's project files

Papers 8816

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42782557PubTator, text miningPubMed
42777063PubTator, text miningPubMed
42742991PubTator, text miningPubMed
42673964PubTator, text miningPubMed
42661044PubTator, text miningPubMed
42658346PubTator, text miningPubMed
42636668PubTator, text miningPubMed
42635405PubTator, text miningPubMed
42625116PubTator, text miningPubMed
42606521PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license