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GNAS: GNAS complex locus

4 proteins, 150 patents, 0 drugs, 0 trials, 4,626 NIH grants and 9,367 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGNASHGNC
NameGNAS complex locusHGNC
NCBI Gene ID2778NCBI Gene
HGNC IDHGNC:4392HGNC
EnsemblENSG00000087460NCBI Gene
AliasesAHO, AIMAH1, C20orf45, GNAS1, GNASXL, GPSA, GSA, GSP, NESP, NESP55, PITA3, POH, SCG6, SgVINCBI Gene
Typeprotein-codingNCBI Gene

Proteins 4

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O95467Neuroendocrine secretory protein 552450Ensembl, GeneID, HGNCUniProt
P63092Guanine nucleotide-binding protein G(s) subunit alpha isoforms short394484Ensembl, GeneID, HGNCUniProt
P84996Protein ALEX6260GeneID, HGNCUniProt
Q5JWF2Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas1,03711Ensembl, GeneID, HGNCUniProt

Patents 150

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026053553 A2026-03-2592P63092Espacenet
JP 2026053553 A2026-03-25141P63092Espacenet
JP 2026004568 A2026-01-1448096O95467Espacenet
JP 2026004568 A2026-01-1448098O95467Espacenet
JP 2026004568 A2026-01-1448100P63092Espacenet
JP 2026004568 A2026-01-1448102O95467Espacenet
JP 2026004568 A2026-01-1448103Q5JWF2Espacenet
EP 4666070 A22025-12-241P63092Espacenet
EP 4650780 A22025-11-198893P63092Espacenet
WO 2025224050 A12025-10-302P63092Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4626

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant902,025NIH's project files
P30CA016672Cancer Center Support Grant702,025NIH's project files
ZIADE000649Skeletal Disorders and Mineral Homeostasis Section582,025NIH's project files
P30CA006973Regional Oncology Research Center332,025NIH's project files
ZIADK043313Role of the Gnas Gene in Metabolic Regulation202,025NIH's project files
ZIADE000380The role of stem cells in skeletal health and disease192,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files
ZIADK043302Studies Of Pseudohypoparathyroidism And Related Disorders162,025NIH's project files
ZIADE000758Metabolic Bone Disorders Unit152,025NIH's project files
R01HL016037Molecular Regulation of Cardiovascular 7 TM Receptors122,025NIH's project files

Papers 9367

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824121PubTator, text miningPubMed
42816363PubTator, text miningPubMed
42810907PubTator, text miningPubMed
42809083PubTator, text miningPubMed
42807753PubTator, text miningPubMed
42794933PubTator, text miningPubMed
42791368PubTator, text miningPubMed
42769834PubTator, text miningPubMed
42755625PubTator, text miningPubMed
42750839PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license